Oral microbiota in human systematic diseases

X Peng, L Cheng, Y You, C Tang, B Ren, Y Li… - International journal of …, 2022 - nature.com
Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The
dynamic oral microbiota cooperates with the host to reflect the information and status of …

Cancer and the microbiome—influence of the commensal microbiota on cancer, immune responses, and immunotherapy

V Matson, CS Chervin, TF Gajewski - Gastroenterology, 2021 - Elsevier
The commensal microbiota has been implicated in the regulation of a diverse array of
physiological processes, both within the gastrointestinal tract and at distant tissue sites …

Molecular Mechanism of Helicobacter pylori-Induced Gastric Cancer

M Alipour - Journal of gastrointestinal cancer, 2021 - Springer
Introduction Various types of cancers threaten human life. The role of bacteria in causing
cancer is controversial, but it has been determined that the Helicobacter pylori infection is …

Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression

R Wang, S Song, J Qin, K Yoshimura, F Peng, Y Chu… - Cancer cell, 2023 - cell.com
Understanding tumor microenvironment (TME) reprogramming in gastric adenocarcinoma
(GAC) progression may uncover novel therapeutic targets. Here, we performed single-cell …

New insights into the cancer–microbiome–immune axis: decrypting a decade of discoveries

T Jain, P Sharma, AC Are, SM Vickers… - Frontiers in …, 2021 - frontiersin.org
The past decade has witnessed groundbreaking advances in the field of microbiome
research. An area where immense implications of the microbiome have been demonstrated …

Interplay between inflammation and cancer

R Khandia, A Munjal - Advances in protein chemistry and structural biology, 2020 - Elsevier
During the 19th century, for the first time, the linkage between inflammation and cancer was
established. Inflammatory microenvironment is an essential component of the tumor …

[HTML][HTML] Helicobacter pylori in human health and disease: Mechanisms for local gastric and systemic effects

D Bravo, A Hoare, C Soto, MA Valenzuela… - World journal of …, 2018 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is present in roughly 50% of the human population worldwide
and infection levels reach over 70% in developing countries. The infection has classically …

Toll-like receptor-guided therapeutic intervention of human cancers: molecular and immunological perspectives

S Mukherjee, R Patra, P Behzadi, A Masotti… - Frontiers in …, 2023 - frontiersin.org
Toll-like receptors (TLRs) serve as the body's first line of defense, recognizing both
pathogen-expressed molecules and host-derived molecules released from damaged or …

Gastric microbes associated with gastric inflammation, atrophy and intestinal metaplasia 1 year after Helicobacter pylori eradication

JJY Sung, OO Coker, E Chu, CH Szeto, STY Luk… - Gut, 2020 - gut.bmj.com
Objective Helicobacter pylori is associated with gastric inflammation, precancerous gastric
atrophy (GA) and intestinal metaplasia (IM). We aimed to identify microbes that are …

Evolution of Diagnostic Methods for Helicobacter pylori Infections: From Traditional Tests to High Technology, Advanced Sensitivity and Discrimination Tools

AI Cardos, A Maghiar, DC Zaha, O Pop, L Fritea… - Diagnostics, 2022 - mdpi.com
Rapid diagnosis and treatment application in the early stages of H. pylori infection plays an
important part in inhibiting the transmission of this infection as this bacterium is involved in …