Thyroid hormone regulation and insulin resistance: insights from animals naturally adapted to fasting
B Martinez, RM Ortiz - Physiology, 2017 - journals.physiology.org
The contribution of thyroidal status in insulin signaling and glucose homeostasis has been
implicated as a potential pathophysiological factor in humans, but the specific mechanisms …
implicated as a potential pathophysiological factor in humans, but the specific mechanisms …
[HTML][HTML] Adiposity and fat metabolism in lactating and fasting northern elephant seals
DE Crocker, CD Champagne, MA Fowler… - Advances in nutrition, 2014 - Elsevier
Several taxa of animals fast completely from food and water during energy-intensive periods
such as lactation, breeding, and development. In elephant seals, these behaviors are …
such as lactation, breeding, and development. In elephant seals, these behaviors are …
Free-swimming northern elephant seals have low field metabolic rates that are sensitive to an increased cost of transport
JL Maresh, SE Simmons, DE Crocker… - Journal of …, 2014 - journals.biologists.com
Widely ranging marine predators often adopt stereotyped, energy-saving behaviours to
minimize the energetic cost of transport while maximizing energy gain. Environmental and …
minimize the energetic cost of transport while maximizing energy gain. Environmental and …
Metabolic responses to adrenocorticotropic hormone (ACTH) vary with life-history stage in adult male northern elephant seals
Strong individual and life-history variation in serum glucocorticoids has been documented in
many wildlife species. Less is known about variation in hypothalamic–pituitary–adrenal …
many wildlife species. Less is known about variation in hypothalamic–pituitary–adrenal …
[HTML][HTML] A non-traditional model of the metabolic syndrome: the adaptive significance of insulin resistance in fasting-adapted seals
Insulin resistance in modern society is perceived as a pathological consequence of excess
energy consumption and reduced physical activity. Its presence in relation to the …
energy consumption and reduced physical activity. Its presence in relation to the …
[HTML][HTML] Summing the strokes: energy economy in northern elephant seals during large-scale foraging migrations
JL Maresh, T Adachi, A Takahashi, Y Naito… - Movement Ecology, 2015 - Springer
Background The energy requirements of free-ranging marine mammals are challenging to
measure due to cryptic and far-ranging feeding habits, but are important to quantify given the …
measure due to cryptic and far-ranging feeding habits, but are important to quantify given the …
Metabolic response of dolphins to short-term fasting reveals physiological changes that differ from the traditional fasting model
Bottlenose dolphins (Tursiops truncatus) typically feed on prey that are high in lipid and
protein content and nearly devoid of carbohydrate, a dietary feature shared with other …
protein content and nearly devoid of carbohydrate, a dietary feature shared with other …
Variation in adrenal and thyroid hormones with life-history stage in juvenile northern elephant seals (Mirounga angustirostris)
The classical approach to quantifying the impact of stressors on wildlife is through
characterization of hormones associated with the generalized stress response. However …
characterization of hormones associated with the generalized stress response. However …
[HTML][HTML] Hepatic ketogenesis is not required for starvation adaptation in mice
K Feola, AH Venable, T Broomfield, M Villegas, X Fu… - Molecular …, 2024 - Elsevier
Objective In response to bacterial inflammation, anorexia of acute illness is protective and is
associated with the induction of fasting metabolic programs such as ketogenesis. Forced …
associated with the induction of fasting metabolic programs such as ketogenesis. Forced …
Oxidative stress in northern elephant seals: Integration of omics approaches with ecological and experimental studies
Northern elephant seals experience conditions that increase oxidative stress (OS), including
extended fasting, ischemia and hypoxia during breath-holds, and immune responses during …
extended fasting, ischemia and hypoxia during breath-holds, and immune responses during …