Fluorescent nucleoside analogues (FNAs) are structurally diverse mimics of the natural
essentially non-fluorescent nucleosides which have found numerous applications in probing …

Recent advances in optical bioimaging have prompted the need for minimal chemical
reporters that can retain the molecular recognition properties and activity profiles of …

The oral administration of the standard cytotoxic agent 5-fluorouracil is extensively limited in
the last three decades. This restriction is due to the drug's uneven intestinal absorption due …

The click azide= alkyne 1, 3-dipolar cycloaddition (click chemistry) has become the
approach of choice for bioconjugations in medicinal chemistry, providing facile reaction …

Abstract Two series of new 1, 2, 3-triazole-purine hybrids were synthesized in considerable
yields (up to 87%), starting from benzyl azides and purine alkynes, via 1, 3-dipolar …

Azido nucleosides have been utilized for click reactions, metabolic incorporation into cellular
DNA, and fluorescent imaging of live cells. Two classes of 6-azido modified uracil …

Described herein is an efficient strategy for assembling a new library of functionalized
polycyclic purinium salts with a wide range of anions through RhIII-catalyzed C–H …

Azido-modified nucleosides have been extensively explored as substrates for click
chemistry and the metabolic labeling of DNA and RNA. These compounds are also of …

Modified bright fluorescent nucleosides that respond to the microenvironment have great
potential as probes. A series of novel 8-(phenylethynyl) phenylated 2-amino-2 …

Pyrimidine‐based derivatives have attracted a lot of interest in heterocyclic chemistry due to
its versatile structure and diverse biological activities. This study provides a comprehensive …