Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment
Risk of cardiovascular (CV) disease is increased among RA patients. High inflammatory
burden associated with RA appears to be a key driver of the increased cardiovascular risk …
burden associated with RA appears to be a key driver of the increased cardiovascular risk …
Exosomes: Revisiting their role as “garbage bags”
M Vidal - Traffic, 2019 - Wiley Online Library
In recent years, the term “extracellular vesicle”(EV) has been used to define different types of
vesicles released by various cells. It includes plasma membrane‐derived vesicles …
vesicles released by various cells. It includes plasma membrane‐derived vesicles …
Human C-reactive protein and the metabolic syndrome
Human C-reactive protein and the metabolic syndrome : Current Opinion in Lipidology Human
C-reactive protein and the metabolic syndrome : Current Opinion in Lipidology Log in or …
C-reactive protein and the metabolic syndrome : Current Opinion in Lipidology Log in or …
The evolving role of C-reactive protein in atherothrombosis
Background: Inflammation is pivotal in all phases of atherosclerosis. Among the numerous
inflammatory biomarkers, the largest amount of published data supports a role for C-reactive …
inflammatory biomarkers, the largest amount of published data supports a role for C-reactive …
Interplay between CRP, atherogenic LDL, and LOX-1 and its potential role in the pathogenesis of atherosclerosis
BACKGROUND Studies have shown that the classic acute-phase protein C-reactive protein
(CRP) has proinflammatory effects on vascular cells and may play a causal role in the …
(CRP) has proinflammatory effects on vascular cells and may play a causal role in the …
Hegemony of inflammation in atherosclerosis and coronary artery disease
Inflammation drives coronary artery disease and atherosclerosis implications. Lipoprotein
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …
[HTML][HTML] The innate immune response to products of phospholipid peroxidation
D Weismann, CJ Binder - Biochimica et Biophysica Acta (BBA) …, 2012 - Elsevier
Lipid peroxidation occurs in the context of many physiological processes but is greatly
increased in various pathological situations. A consequence of phospholipid peroxidation is …
increased in various pathological situations. A consequence of phospholipid peroxidation is …
[HTML][HTML] Sex hormone modulation of proinflammatory cytokine and CRP expression in macrophages from older men and postmenopausal women
MP Corcoran, M Meydani, AH Lichtenstein… - The Journal of …, 2010 - ncbi.nlm.nih.gov
Inflammation plays a central role in the development and progression of coronary heart
disease (CHD). The sex hormones estrogen and testosterone have been shown to modify …
disease (CHD). The sex hormones estrogen and testosterone have been shown to modify …
Human C-reactive protein induces endothelial dysfunction and uncoupling of eNOS in vivo
BACKGROUND AND OBJECTIVE: Elevated C-reactive protein (CRP) levels are associated
with increased cardiovascular events and endothelial dysfunction. We have previously …
with increased cardiovascular events and endothelial dysfunction. We have previously …
C-reactive protein polarizes human macrophages to an M1 phenotype and inhibits transformation to the M2 phenotype
Objective—Inflammation is pivotal in atherosclerosis. Monocyte-macrophages are crucial in
atherosclerosis. Monocytes can develop into subsets: classically (M1) or alternatively (M2) …
atherosclerosis. Monocytes can develop into subsets: classically (M1) or alternatively (M2) …