[HTML][HTML] Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment

V Rajeev, DY Fann, QN Dinh, HA Kim, TM De Silva… - Theranostics, 2022 - ncbi.nlm.nih.gov
The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …

CNS small vessel disease: a clinical review

RJ Cannistraro, M Badi, BH Eidelman, DW Dickson… - Neurology, 2019 - AAN Enterprises
CNS small vessel disease (CSVD) causes 25% of strokes and contributes to 45% of
dementia cases. Prevalence increases with age, affecting about 5% of people aged 50 …

[HTML][HTML] Cerebral small vessel disease: A review

J Chojdak-Łukasiewicz, E Dziadkowiak… - … in Clinical and …, 2021 - advances.umw.edu.pl
Cerebral small vessel disease (CSVD) is the most common, chronic and progressive
vascular disease. The changes affect arterioles, capillaries and small veins supplying the …

Chronic cerebral hypoperfusion: a critical feature in unravelling the etiology of vascular cognitive impairment

V Rajeev, YL Chai, L Poh, S Selvaraji, DY Fann… - Acta neuropathologica …, 2023 - Springer
Vascular cognitive impairment (VCI) describes a wide spectrum of cognitive deficits related
to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically …

Parkinson's disease in the Western Pacific Region

SY Lim, AH Tan, A Ahmad-Annuar, C Klein… - The Lancet …, 2019 - thelancet.com
Summary 1· 8 billion people of diverse ethnicities and cultures live in the Western Pacific
Region. The increasing longevity of populations in this region is a major contributor to the …

Cerebral small vessel disease: a review of the pathophysiological mechanisms

Y Hannawi - Translational Stroke Research, 2024 - Springer
Cerebral small vessel disease (cSVD) refers to the age-dependent pathological processes
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …

The global burden of cerebral small vessel disease in low-and middle-income countries: A systematic review and meta-analysis

BYK Lam, Y Cai, R Akinyemi… - … Journal of Stroke, 2023 - journals.sagepub.com
Background: Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia.
Previous studies on the prevalence of cSVD are mostly based on single geographically …

[HTML][HTML] Prevalence and risk factors of cerebral small vessel disease in a Chinese population-based sample

F Han, FF Zhai, Q Wang, LX Zhou, J Ni, M Yao… - Journal of …, 2018 - ncbi.nlm.nih.gov
Background and Purpose Epidemiological data of cerebral small vessel disease (CSVD) in
the general population of China are lacking. We report on the prevalence of lacunes, white …

Broad phenotype of cysteine-altering NOTCH3 variants in UK Biobank: CADASIL to nonpenetrance

JW Rutten, RJ Hack, M Duering, G Gravesteijn… - Neurology, 2020 - AAN Enterprises
Objective To determine the small vessel disease spectrum associated with cysteine-altering
NOTCH3 variants in community-dwelling individuals by analyzing the clinical and …

Enlarged perivascular spaces and cognition: a meta-analysis of 5 population-based studies

S Hilal, CS Tan, HHH Adams, M Habes, V Mok… - Neurology, 2018 - AAN Enterprises
Objective To investigate the association of enlarged perivascular spaces (ePVS) with
cognition in elderly without dementia. Methods We included 5 studies from the Uniform …