Predicting upper limb motor impairment recovery after stroke: a mixture model

R van der Vliet, RW Selles… - Annals of …, 2020 - Wiley Online Library
Objective Spontaneous recovery is an important determinant of upper extremity recovery
after stroke and has been described by the 70% proportional recovery rule for the Fugl …

Post-stroke outcomes predicted from multivariate lesion-behaviour and lesion network mapping

M Bowren Jr, J Bruss, K Manzel, D Edwards, C Liu… - Brain, 2022 - academic.oup.com
Clinicians and scientists alike have long sought to predict the course and severity of chronic
post-stroke cognitive and motor outcomes, as the ability to do so would inform treatment and …

Principles and requirements for stroke recovery science

CJ Sommer, WR Schäbitz - Journal of Cerebral Blood Flow & …, 2021 - journals.sagepub.com
The disappointing results in bench-to-bedside translation of neuroprotective strategies
caused a certain shift in stroke research towards enhancing the endogenous recovery …

Is recovery of somatosensory impairment conditional for upper-limb motor recovery early after stroke?

SB Zandvliet, G Kwakkel, RHM Nijland… - … and neural repair, 2020 - journals.sagepub.com
Background. Spontaneous recovery early after stroke is most evident during a time-sensitive
window of heightened neuroplasticity, known as spontaneous neurobiological recovery. It is …

Segmental motor recovery after cervical spinal cord injury relates to density and integrity of corticospinal tract projections

G Balbinot, G Li, S Kalsi-Ryan, R Abel, D Maier… - Nature …, 2023 - nature.com
Cervical spinal cord injury (SCI) causes extensive impairments for individuals which may
include dextrous hand function. Although prior work has focused on the recovery at the …

Assessment of neurological impairment and recovery using statistical models of neurologically healthy behavior

SH Scott, CR Lowrey, IE Brown… - … and Neural Repair, 2023 - journals.sagepub.com
While many areas of medicine have benefited from the development of objective
assessment tools and biomarkers, there have been comparatively few improvements in …

Individualized response to semantic versus phonological aphasia therapies in stroke

S Kristinsson, A Basilakos, J Elm, LA Spell… - Brain …, 2021 - academic.oup.com
Attempts to personalize aphasia treatment to the extent where it is possible to reliably predict
individual response to a particular treatment have yielded inconclusive results. The current …

Inpatient stroke rehabilitation: prediction of clinical outcomes using a machine-learning approach

Y Harari, MK O'Brien, RL Lieber… - … of neuroengineering and …, 2020 - Springer
Background In clinical practice, therapists often rely on clinical outcome measures to
quantify a patient's impairment and function. Predicting a patient's discharge outcome using …

Bringing proportional recovery into proportion: Bayesian modelling of post-stroke motor impairment

AK Bonkhoff, T Hope, D Bzdok, AG Guggisberg… - Brain, 2020 - academic.oup.com
Accurate predictions of motor impairment after stroke are of cardinal importance for the
patient, clinician, and healthcare system. More than 10 years ago, the proportional recovery …

Arguments for the biological and predictive relevance of the proportional recovery rule

J Goldsmith, T Kitago, AG de la Garza, R Kundert… - Elife, 2022 - elifesciences.org
The proportional recovery rule (PRR) posits that most stroke survivors can expect to reduce
a fixed proportion of their motor impairment. As a statistical model, the PRR explicitly relates …