Spheroids and organoids are important novel players in medical and life science research.
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …

Three-dimensional multicellular tumor models are receiving an ever-growing focus as
preclinical drug-screening platforms due to their potential to recapitulate major physiological …

Culture medium is frequently modelled as water in computational fluid dynamics (CFD)
analysis of in vitro culture systems involving flow, such as bioreactors and organ-on-chips …

Magnetic levitational bioassembly of three-dimensional (3D) tissue constructs represents a
rapidly emerging scaffold-and label-free approach and alternative conceptual advance in …

Abstract Three-dimensional (3D) cell culture has tremendous advantages to closely mimic
the in vivo architecture and microenvironment of healthy tissue and organs, as well as of …

The constant supply of high cell numbers generated by defined, robust, and economically
viable culture processes is indispensable for the envisioned application of human …

Background and Aims The gap between patients on transplant waiting lists and available
donor organs is steadily increasing. Human organoids derived from leucine‐rich repeat …

Cancer still ranks as a leading cause of mortality worldwide. Although considerable efforts
have been dedicated to anticancer therapeutics, progress is still slow, partially due to the …

Two-dimensional (2D) cell culture techniques are commonly employed to investigate
biophysical and biochemical cellular responses. However, these culture methods, having …

Spheroid culture provides cells with a three‐dimensional environment that can better mimic
physiological conditions compared to monolayer culture. Technologies involved in the …