Towards better clinical prediction models: seven steps for development and an ABCD for validation
EW Steyerberg, Y Vergouwe - European heart journal, 2014 - academic.oup.com
Clinical prediction models provide risk estimates for the presence of disease (diagnosis) or
an event in the future course of disease (prognosis) for individual patients. Although …
an event in the future course of disease (prognosis) for individual patients. Although …
[HTML][HTML] State of the art in selection of variables and functional forms in multivariable analysis—outstanding issues
W Sauerbrei, A Perperoglou, M Schmid… - … and prognostic research, 2020 - Springer
Background How to select variables and identify functional forms for continuous variables is
a key concern when creating a multivariable model. Ad hoc 'traditional'approaches to …
a key concern when creating a multivariable model. Ad hoc 'traditional'approaches to …
Calculating the sample size required for developing a clinical prediction model
Clinical prediction models aim to predict outcomes in individuals, to inform diagnosis or
prognosis in healthcare. Hundreds of prediction models are published in the medical …
prognosis in healthcare. Hundreds of prediction models are published in the medical …
Minimum sample size for developing a multivariable prediction model: PART II‐binary and time‐to‐event outcomes
When designing a study to develop a new prediction model with binary or time‐to‐event
outcomes, researchers should ensure their sample size is adequate in terms of the number …
outcomes, researchers should ensure their sample size is adequate in terms of the number …
Sample size for binary logistic prediction models: beyond events per variable criteria
M van Smeden, KGM Moons… - … methods in medical …, 2019 - journals.sagepub.com
Binary logistic regression is one of the most frequently applied statistical approaches for
developing clinical prediction models. Developers of such models often rely on an Events …
developing clinical prediction models. Developers of such models often rely on an Events …
Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration
KGM Moons, DG Altman, JB Reitsma… - Annals of internal …, 2015 - acpjournals.org
The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …
Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …
Prediction of obstructive coronary artery disease and prognosis in patients with suspected stable angina
J Reeh, CB Therming, M Heitmann… - European heart …, 2019 - academic.oup.com
Aims We hypothesized that the modified Diamond–Forrester (DF) prediction model
overestimates probability of coronary artery disease (CAD). The aim of this study was to …
overestimates probability of coronary artery disease (CAD). The aim of this study was to …
Evaluating the risk of ovarian cancer before surgery using the ADNEX model to differentiate between benign, borderline, early and advanced stage invasive, and …
B Van Calster, K Van Hoorde, L Valentin, AC Testa… - Bmj, 2014 - bmj.com
Objectives To develop a risk prediction model to preoperatively discriminate between
benign, borderline, stage I invasive, stage II-IV invasive, and secondary metastatic ovarian …
benign, borderline, stage I invasive, stage II-IV invasive, and secondary metastatic ovarian …
Minimum sample size for developing a multivariable prediction model: Part I–Continuous outcomes
In the medical literature, hundreds of prediction models are being developed to predict
health outcomes in individuals. For continuous outcomes, typically a linear regression model …
health outcomes in individuals. For continuous outcomes, typically a linear regression model …
Assessing the performance of prediction models: a framework for traditional and novel measures
The performance of prediction models can be assessed using a variety of methods and
metrics. Traditional measures for binary and survival outcomes include the Brier score to …
metrics. Traditional measures for binary and survival outcomes include the Brier score to …