Platelet-rich plasma versus hyaluronic acid for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials

JW Belk, MJ Kraeutler, DA Houck… - … American journal of …, 2021 - journals.sagepub.com
Background: Platelet-rich plasma (PRP) and hyaluronic acid (HA) are 2 nonoperative
treatment options for knee osteoarthritis (OA) that are supposed to provide symptomatic …

Efficacy of intra-articular platelet-rich plasma injections in knee osteoarthritis: a systematic review

CJ Meheux, PC McCulloch, DM Lintner… - … : The Journal of …, 2016 - Elsevier
Purpose To determine (1) whether platelet-rich plasma (PRP) injection significantly
improves validated patient-reported outcomes in patients with symptomatic knee …

A composite hydrogel with co-delivery of antimicrobial peptides and platelet-rich plasma to enhance healing of infected wounds in diabetes

S Wei, P Xu, Z Yao, X Cui, X Lei, L Li, Y Dong, W Zhu… - Acta biomaterialia, 2021 - Elsevier
Diabetic wound healing remains a major challenge due to its vulnerability to bacterial
infection, as well as the less vascularization and prolonged inflammatory phase. In this …

Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors

PR Amable, RBV Carias, MVT Teixeira… - Stem cell research & …, 2013 - Springer
Introduction Platelet-rich plasma (PRP) is nowadays widely applied in different clinical
scenarios, such as orthopedics, ophthalmology and healing therapies, as a growth factor …

Multiple PRP injections are more effective than single injections and hyaluronic acid in knees with early osteoarthritis: a randomized, double-blind, placebo-controlled …

G Görmeli, CA Görmeli, B Ataoglu, C Çolak… - Knee Surgery, Sports …, 2017 - Springer
Purpose To compare the effectiveness of intraarticular (IA) multiple and single platelet-rich
plasma (PRP) injections as well as hyaluronic acid (HA) injections in different stages of …

Exosomes derived from platelet-rich plasma administration in site mediate cartilage protection in subtalar osteoarthritis

Y Zhang, X Wang, J Chen, D Qian, P Gao, T Qin… - Journal of …, 2022 - Springer
Subtalar osteoarthritis (STOA) is often secondary to chronic ankle sprains, which seriously
affects the quality of life of patients. Due to its etiology and pathogenesis was not studied …

Platelet-rich plasma for managing pain and inflammation in osteoarthritis

I Andia, N Maffulli - Nature Reviews Rheumatology, 2013 - nature.com
Osteoarthritis (OA) is a common disease involving joint damage, an inadequate healing
response and progressive deterioration of the joint architecture. Autologous blood-derived …

[HTML][HTML] Platelet rich plasma (PRP) induces chondroprotection via increasing autophagy, anti-inflammatory markers, and decreasing apoptosis in human osteoarthritic …

M Moussa, D Lajeunesse, G Hilal, O El Atat… - Experimental cell …, 2017 - Elsevier
Objectives Autophagy constitutes a defense mechanism to overcome aging and apoptosis in
osteoarthritic cartilage. Several cytokines and transcription factors are linked to autophagy …

Intra-articular injections of platelet-rich plasma, hyaluronic acid or corticosteroids for knee osteoarthritis: A prospective randomized controlled study.

Y Huang, X Liu, X Xu, J Liu - Der Orthopade, 2019 - europepmc.org
Background Knee osteoarthritis (KOA) is a degenerative joint disease leading to pain and
disability for which no curative treatment exists. Intra-articular (IA) therapies are part of this …

A randomized clinical trial evaluating plasma rich in growth factors (PRGF-Endoret) versus hyaluronic acid in the short-term treatment of symptomatic knee …

M Sánchez, N Fiz, J Azofra, J Usabiaga… - … : The Journal of …, 2012 - Elsevier
PURPOSE: This multicenter, double-blind clinical trial evaluated and compared the efficacy
and safety of PRGF-Endoret (BTI Biotechnology Institute, Vitoria-Gasteiz, Spain), an …