HLA alleles are functionally relevant. Unrelated HCT can be optimized by comprehensive
and precise donor-recipient allele matching. For patients with high-risk diseases who lack …

Outcome of unrelated donor marrow transplantation is influenced by donor-recipient
matching for HLA. Prior studies assessing the effects of mismatches at specific HLA loci …

The demand for unrelated haematopoietic cell (HPC) donors has risen threefold over the
last decade, and is likely to continue to rise over the next 10 years. The time taken from …

The importance of HLA-DPB1 matching for the outcome of allogeneic hematologic stem cell
(HSC) transplantation is controversial. We have previously identified HLA-DPB1* 0901 as a …

HLA matching between the donor and recipient improves the success of unrelated
hematopoietic stem cell transplantation (HSCT). Because many patients in need of an …

Hematopoietic cell transplantation (HCT) from an HLA-A, HLA-B, HLA-C, HLA-DRB1, and
HLA-DQB1 allele–matched unrelated donor is a well-recognized life-saving treatment …

Although it has been over 25 years since HLA‐DP was mapped to the major
histocompatibility complex (MHC), its biological functions remain ill‐defined. We sought to …

Abstract CD8+ T cell–depleted (TCD) donor lymphocyte infusion (DLI) after TCD allogeneic
hematopoietic stem cell transplantation (alloSCT) has been associated with a reduced risk …

Studies in unrelated donor (UD) hematopoietic stem cell transplantations (HSCT) show an
effect of the matching status of HLA-DPB1 on complications. We analyzed 423 UD-HSCT …

Graft-versus-host disease (GVHD) is a potentially life-threatening complication of allogeneic
hematopoietic cell transplantation. Many genes are presumed to be involved in GVHD, but …