Pathogenesis of triple-negative breast cancer

F Derakhshan, JS Reis-Filho - Annual Review of Pathology …, 2022 - annualreviews.org
Triple-negative breast cancer (TNBC) encompasses a heterogeneous group of
fundamentally different diseases with different histologic, genomic, and immunologic …

Overview of multiplex immunohistochemistry/immunofluorescence techniques in the era of cancer immunotherapy

WCC Tan, SN Nerurkar, HY Cai, HHM Ng… - Cancer …, 2020 - Wiley Online Library
Conventional immunohistochemistry (IHC) is a widely used diagnostic technique in tissue
pathology. However, this technique is associated with a number of limitations, including high …

Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation

T Popova, E Manié, G Rieunier, V Caux-Moncoutier… - Cancer research, 2012 - AACR
BRCA1 inactivation is a frequent event in basal-like breast carcinomas (BLC). However,
BRCA1 can be inactivated by multiple mechanisms and determining its status is not a trivial …

[HTML][HTML] Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists

S Badve, DJ Dabbs, SJ Schnitt, FL Baehner, T Decker… - Modern pathology, 2011 - Elsevier
Breast cancer is a heterogeneous disease encompassing a variety of entities with distinct
morphological features and clinical behaviors. Although morphology is often associated with …

[HTML][HTML] Histological types of breast cancer: how special are they?

B Weigelt, FC Geyer, JS Reis-Filho - Molecular oncology, 2010 - Elsevier
Breast cancer is a heterogeneous disease, comprising multiple entities associated with
distinctive histological and biological features, clinical presentations and behaviours and …

Gene-expression signatures in breast cancer

C Sotiriou, L Pusztai - New England Journal of Medicine, 2009 - Mass Medical Soc
This review discusses the results of DNA microarray signatures in breast cancer. These
signatures have been useful in the classification of breast cancers, and they have an …

Basal-like breast cancer: a critical review

EA Rakha, JS Reis-Filho, IO Ellis - Journal of clinical oncology, 2008 - ascopubs.org
Recent gene expression profiling of breast cancer has identified specific subtypes with
clinical, biologic, and therapeutic implications. The basal-like group of tumors is …

Triple negative tumours: a critical review

JS Reis‐Filho, ANJ Tutt - Histopathology, 2008 - Wiley Online Library
Breast cancer is a heterogeneous disease that encompasses several distinct entities with
remarkably different biological characteristics and clinical behaviour. Currently, breast …

Histological and molecular types of breast cancer: is there a unifying taxonomy?

B Weigelt, JS Reis-Filho - Nature reviews Clinical oncology, 2009 - nature.com
Breast cancer is a complex and heterogeneous disease, comprising multiple tumor entities
associated with distinctive histological patterns and different biological features and clinical …

Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity

F Chibon, P Lagarde, S Salas, G Pérot, V Brouste… - Nature medicine, 2010 - nature.com
Sarcomas are heterogeneous and aggressive mesenchymal tumors. Histological grading
has so far been the best predictor for metastasis-free survival, but it has several limitations …