The global adoption of artemisinin-based combination therapies (ACTs) in the early 2000s
heralded a new era in effectively treating drug-resistant Plasmodium falciparum malaria …

A marked decrease in malaria-related deaths worldwide has been attributed to the
administration of effective antimalarials against Plasmodium falciparum, in particular …

Increasing antimalarial drug resistance once again threatens effective antimalarial drug
treatment, malaria control, and elimination. Artemisinin combination therapies (ACTs) are …

Background Artemisinin resistance in Plasmodium falciparum has emerged in Southeast
Asia and now poses a threat to the control and elimination of malaria. Mapping the …

Background Recent gains in reducing the global burden of malaria are threatened by the
emergence of Plasmodium falciparum resistance to artemisinins. The discovery that …

Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens
malaria control and elimination activities worldwide. To monitor the spread of artemisinin …

Background A multidrug-resistant co-lineage of Plasmodium falciparum malaria, named
KEL1/PLA1, spread across Cambodia in 2008–13, causing high rates of treatment failure …

Artemisinins are the cornerstone of anti-malarial drugs. Emergence and spread of resistance
to them,, raises risk of wiping out recent gains achieved in reducing worldwide malaria …

We report a large multicenter genome-wide association study of Plasmodium falciparum
resistance to artemisinin, the frontline antimalarial drug. Across 15 locations in Southeast …

Background As the prevalence of artemisinin-resistant Plasmodium falciparum malaria
increases in the Greater Mekong subregion, emerging resistance to partner drugs in …