Cancer stem cells in oral cavity squamous cell carcinoma: a review

R Baillie, ST Tan, T Itinteang - Frontiers in Oncology, 2017 - frontiersin.org
Cancer stem cells (CSCs) have been identified in oral cavity squamous cell carcinoma
(OCSCC). CSCs possess the ability for perpetual self-renewal and proliferation, producing …

Oral epithelial stem cells in tissue maintenance and disease: the first steps in a long journey

KB Jones, OD Klein - International journal of oral science, 2013 - nature.com
The identification and characterization of stem cells is a major focus of developmental
biology and regenerative medicine. The advent of genetic inducible fate mapping …

[HTML][HTML] CD44highCD24low molecular signature determines the cancer stem cell and EMT phenotype in oral squamous cell carcinoma

S Ghuwalewala, D Ghatak, P Das, S Dey, S Sarkar… - Stem cell …, 2016 - Elsevier
Almost all epithelial tumours contain cancer stem-like cells, which possess a unique
property of self-renewal and differentiation. In oral cancer, several biomarkers including cell …

Nonadhesive culture system as a model of rapid sphere formation with cancer stem cell properties

SF Chen, YC Chang, S Nieh, CL Liu, CY Yang, YS Lin - PloS one, 2012 - journals.plos.org
Background Cancer stem cells (CSCs) play an important role in tumor initiation, progression,
and metastasis and are responsible for high therapeutic failure rates. Identification and …

Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer

N Sinha, S Mukhopadhyay, DN Das, PK Panda… - Oral oncology, 2013 - Elsevier
Oral squamous cell carcinoma (OSCC) acquires the top most position among the other
malignancies and patients die with this disease complication within 5 years. One of the …

[HTML][HTML] Head and neck cancer management and cancer stem cells implication

OA Elkashty, R Ashry, SD Tran - The Saudi Dental Journal, 2019 - Elsevier
Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are heterogeneous in nature. Risk factors for HNSCCs are …

Side population cells as prototype of chemoresistant, tumor‐initiating cells

V Richard, MG Nair… - BioMed research …, 2013 - Wiley Online Library
Classically, isolation of CSCs from tumors exploits the detection of cell surface markers
associated with normal stem cells. Invariable expression of these cell surface markers in …

Pancreatic ductal adenocarcinoma cell lines display a plastic ability to bi‑directionally convert into cancer stem cells

E Dalla Pozza, I Dando… - International …, 2015 - spandidos-publications.com
Pancreatic ductal adenocarcinoma (PDAC) is often diagnosed when metastatic events have
occurred. Cancer stem cells (CSCs) play an important role in tumor initiation, metastasis …

Targeting CD133 in the enhancement of chemosensitivity in oral squamous cell carcinoma–derived side population cancer stem cells

CC Yu, FW Hu, CH Yu, MY Chou - Head & neck, 2016 - Wiley Online Library
Background Oral squamous cell carcinoma (OSCC) is one of the most common cancers in
the world. Previously, we enriched a subpopulation of OSCC‐derived cancer stem cells …

[PDF][PDF] Molecular mechanisms of chemoresistance in oral cancer

C Wang, XQ Liu, JS Hou, JN Wang, HZ Huang - Chin J Dent Res, 2016 - cjdr.cndent.com
Oral cancer is an aggressive disease with the propensity for local recurrence and distal
metastasis in the head and neck region. Currently, cisplatin-based chemotherapy or …