Electrolyte transport in the mammalian colon: mechanisms and implications for disease

K Kunzelmann, M Mall - Physiological reviews, 2002 - journals.physiology.org
The colonic epithelium has both absorptive and secretory functions. The transport is
characterized by a net absorption of NaCl, short-chain fatty acids (SCFA), and water …

A look at the smelly side of physiology: transport of short chain fatty acids

F Stumpff - Pflügers Archiv-European Journal of Physiology, 2018 - Springer
Fermentative organs such as the caecum, the colon, and the rumen have evolved to
produce and absorb energy rich short chain fatty acids (SCFA) from otherwise indigestible …

Mechanisms of acid and base secretion by the airway epithelium

H Fischer, JH Widdicombe - The Journal of membrane biology, 2006 - Springer
One of the main functions of the airway epithelium is to inactivate and remove infectious
particles from inhaled air and thereby prevent infection of the distal lung. This function is …

Hydrolysis and absorption in the small intestines of posthatch chicks

D Sklan, Y Noy - Poultry science, 2000 - Elsevier
In the immediate posthatch period, chicks must transfer from metabolic dependence on yolk
to utilization of exogenous feed. This study describes changes in intestinal luminal …

Acid-base disturbances in gastrointestinal disease

FJ Gennari, WJ Weise - Clinical Journal of the American Society of …, 2008 - journals.lww.com
Disruption of normal gastrointestinal function as a result of infection, hereditary or acquired
diseases, or complications of surgical procedures uncovers its important role in acid-base …

Proton pump inhibitors: actions and reactions

JM Mullin, M Gabello, LJ Murray, CP Farrell… - Drug discovery today, 2009 - Elsevier
Proton pump inhibitors are the second most commonly prescribed drug class in the United
States. The increased utilization of PPIs parallels the rising incidence of reflux disease …

[HTML][HTML] Isolation and characterization of a cDNA encoding the putative distal colon H+, K (+)-ATPase. Similarity of deduced amino acid sequence to gastric H+, K (+) …

MS Crowson, GE Shull - Journal of Biological Chemistry, 1992 - Elsevier
A series of Northern blot hybridization experiments using probes derived from the rat gastric
H+, K (+)-ATPase cDNA and the human ATP1AL1 gene revealed the presence of a 4.3 …

Increased sensitivity to K+ deprivation in colonic H, K-ATPase-deficient mice.

P Meneton, PJ Schultheis, J Greeb… - The Journal of …, 1998 - Am Soc Clin Investig
Previous studies using isolated tissues suggest that the colonic H, K-ATPase (cHKA),
expressed in the colon and kidney, plays an important role in K+ conservation. To test the …

Colonic potassium handling

MV Sorensen, JE Matos, HA Praetorius… - Pflügers Archiv-European …, 2010 - Springer
Homeostatic control of plasma K+ is a necessary physiological function. The daily dietary K+
intake of~ 100 mmol is excreted predominantly by the distal tubules of the kidney. About …

H+-K+-ATPases: regulation and role in pathophysiological states

RB Silver, M Soleimani - American Journal of Physiology …, 1999 - journals.physiology.org
Molecular cloning experiments have identified the existence of two H+-K+-ATPases (HKAs),
colonic and gastric. Recent functional and molecular studies indicate the presence of both …