Disrupted sleep and circadian rhythms in schizophrenia and their interaction with dopamine signaling

A Ashton, A Jagannath - Frontiers in neuroscience, 2020 - frontiersin.org
Sleep and circadian rhythm disruption (SCRD) is a common feature of schizophrenia, and is
associated with symptom severity and patient quality of life. It is commonly manifested as …

Melatonergic agents influence the sleep-wake and circadian rhythms in healthy and psychiatric participants: a systematic review and meta-analysis of randomized …

E Moon, T Partonen, S Beaulieu… - …, 2022 - nature.com
Exogenous melatonergic agents are widely used to treat insomnia and sleep disturbance.
Several studies have shown that they might also modulate circadian rhythms. The purpose …

[HTML][HTML] Therapeutic use of melatonin in schizophrenia: A systematic review

C Duan, ZM Jenkins, D Castle - World Journal of Psychiatry, 2021 - ncbi.nlm.nih.gov
BACKGROUND Sleep dysfunction is a common problem in people with schizophrenia, and
side effects of treatment often exacerbate metabolic and cardiovascular risk and may induce …

Are circadian disturbances a core pathophysiological component of schizophrenia?

TC Delorme, LK Srivastava… - Journal of Biological …, 2020 - journals.sagepub.com
Schizophrenia is a multifactorial disorder caused by a combination of genetic variations and
exposure to environmental insults. Sleep and circadian rhythm disturbances are a prominent …

Hormone targets for the treatment of sleep disorders in postmenopausal women with schizophrenia: a narrative review

A González-Rodríguez, J Haba-Rubio, J Usall… - Clocks & Sleep, 2022 - mdpi.com
While the early identification of insomnia in patients with schizophrenia is of clinical
relevance, the use of specific compounds to treat insomnia has been studied less in …

A mixed methods expert opinion study on the optimal content and format for an occupational therapy intervention to improve sleep in schizophrenia spectrum …

SM Faulkner, RJ Drake, M Ogden, M Gardani, PE Bee - Plos one, 2022 - journals.plos.org
Introduction People with schizophrenia spectrum disorder diagnoses commonly have poor
sleep, which predicts various negative outcomes. The problems are diverse, including …

Eveningness chronotype preference among individuals at clinical high risk for psychosis

JR Lunsford-Avery, A Pelletier-Baldelli, SA Korenic… - Schizophrenia …, 2021 - Elsevier
Background Circadian rhythm disturbances are frequently implicated in psychosis. Indeed,
research has suggested several avenues by which circadian rhythms may play a …

The circadian system: A neglected player in neurodevelopmental disorders

AA Bouteldja, D Penichet, LK Srivastava… - European Journal of …, 2024 - Wiley Online Library
Patients with neurodevelopmental disorders, such as autism spectrum disorder, often
display abnormal circadian rhythms. The role of the circadian system in these disorders has …

Modulation of neural circuits by melatonin in neurodegenerative and neuropsychiatric disorders

A Giri, S Mehan, Z Khan, G Das Gupta… - Naunyn-Schmiedeberg's …, 2024 - Springer
Neurodegenerative and neuropsychiatric disorders are two broad categories of neurological
disorders characterized by progressive impairments in movement and cognitive functions …

Prevalence of circadian rhythm sleep-wake disorder in outpatients with schizophrenia and its association with psychopathological characteristics and psychosocial …

K Matsui, K Inada, K Kuriyama, T Yoshiike… - Journal of Clinical …, 2021 - mdpi.com
The prevalence of circadian rhythm sleep-wake disorder (CRSWD) among patients with
schizophrenia is not clear. The effect of comorbid CRSWD on such patients has also not …