Nanocrystals of poorly soluble drugs: drug bioavailability and physicochemical stability
Many approaches have been developed over time to overcome the bioavailability limitations
of poorly soluble drugs. With the advances in nanotechnology in recent decades, science …
of poorly soluble drugs. With the advances in nanotechnology in recent decades, science …
[HTML][HTML] Nanocrystals for enhancement of oral bioavailability of poorly water-soluble drugs
VB Junyaprasert, B Morakul - Asian journal of pharmaceutical sciences, 2015 - Elsevier
Nanocrystals, a carrier-free colloidal delivery system in nano-sized range, is an interesting
approach for poorly soluble drugs. Nanocrystals provide special features including …
approach for poorly soluble drugs. Nanocrystals provide special features including …
Physical and chemical stability of drug nanoparticles
L Wu, J Zhang, W Watanabe - Advanced drug delivery reviews, 2011 - Elsevier
As nano-sizing is becoming a more common approach for pharmaceutical product
development, researchers are taking advantage of the unique inherent properties of …
development, researchers are taking advantage of the unique inherent properties of …
Bottom-up approaches for preparing drug nanocrystals: formulations and factors affecting particle size
B Sinha, RH Müller, JP Möschwitzer - International journal of pharmaceutics, 2013 - Elsevier
The solubility dependent bioavailability problem has become a major hurdle in drug
development processes. Drug nanocrystals have been widely accepted by the …
development processes. Drug nanocrystals have been widely accepted by the …
Stability of nanosuspensions in drug delivery
Y Wang, Y Zheng, L Zhang, Q Wang… - Journal of controlled …, 2013 - Elsevier
Nanosuspensions are nanosized colloidal dispersion systems that are stabilized by
surfactants and/or polymers. Because nanosizing results in the creation of new interfaces …
surfactants and/or polymers. Because nanosizing results in the creation of new interfaces …
Emerging role of nanosuspensions in drug delivery systems
Rapid advancement in drug discovery process is leading to a number of potential new drug
candidates having excellent drug efficacy but limited aqueous solubility. By virtue of the …
candidates having excellent drug efficacy but limited aqueous solubility. By virtue of the …
Liquid antisolvent precipitation and stabilization of nanoparticles of poorly water soluble drugs in aqueous suspensions: Recent developments and future perspective
The liquid antisolvent (LAS) precipitation process for production of ultra-fine particles has
been widely researched for a last few decades. In LAS process, precipitation of solute is …
been widely researched for a last few decades. In LAS process, precipitation of solute is …
[HTML][HTML] Nanosuspensions technology as a master key for nature products drug delivery and in vivo fate
Y Ma, Z Cong, P Gao, Y Wang - European Journal of Pharmaceutical …, 2023 - Elsevier
The drug nanosuspensions is a universal formulation approach for improved drug delivery
of hydrophobic drugs and one the most promising approaches for increasing the …
of hydrophobic drugs and one the most promising approaches for increasing the …
Stabilizing agents for drug nanocrystals: effect on bioavailability
A Tuomela, J Hirvonen, L Peltonen - Pharmaceutics, 2016 - mdpi.com
Drug nanocrystals are a versatile option for drug delivery purposes, and while the number of
poorly soluble drug materials is all the time increasing, more research in this area is …
poorly soluble drug materials is all the time increasing, more research in this area is …
A review on novel methodologies for drug nanoparticle preparation: Microfluidic approach
The intrinsic limitations of conventional dosages have facilitated the emergence of novel
drug delivery methodologies. Drug nanonization and encapsulation in polymeric …
drug delivery methodologies. Drug nanonization and encapsulation in polymeric …