Chronic hyperglycemia initiates multiple pathways that contribute to developing
complications in individuals with diabetes, ultimately leading to significant health problems …

Diabetic nephropathy (DN) is a major healthcare challenge for individuals with diabetes and
associated with increased cardiovascular morbidity and mortality. The existing rodent …

Three-dimensional bioprinting technology provides a promising platform to fabricate living
neural systems with inherent spatial and biological complexity. However, the encapsulated …

Cataract is an eye disease, in which the lens becomes opaque, causing vision loss and
blindness. The detailed mechanism of cataract development has not been characterized …

Research on the pathogenesis of cataracts is ongoing and the number of publications on
this topic is increasing annually. This study offers an overview of the research status, popular …

AIM To explore whether autophagy functions as a cellular adaptation mechanism in lens
epithelial cells (LECs) under hyperosmotic stress. METHODS LECs were treated with …

Diabetic retinopathy (DR) is a debilitating organ manifestation of diabetes. Absent of early
diagnosis and intervention, vision tends to drastically and irreversibly decline. Previously …

Regulation of ion and water microcirculation within the lens is tightly controlled through
aquaporin channels and connexin junctions. However, cataracts can occur when the lens …

The gestational period, spanning approximately 40 weeks from fertilization to birth, is pivotal
in human reproduction. Monitoring the health of pregnant women and newborns during this …

Cataract in type-2 diabetes (T2D) patients is a secondary complication and one of the
leading causes of vision loss next to diabetic retinopathy. Various factors such as age …