Current progress and challenges of immunotherapy in gastric cancer: A focus on CAR-T cells therapeutic approach

M Entezam, MJ Sanaei, Y Mirzaei, AH Mer… - Life sciences, 2023 - Elsevier
Gastric cancer (GC) is a severe malignancy, accounting for the third most common cancer
death worldwide. Despite the development of chemo-radiation therapy, there has not been …

Recent advances in immune therapies for gastric cancer

MJ Olnes, HA Martinson - Cancer gene therapy, 2021 - nature.com
Gastric cancer (GC) is an aggressive malignancy that is the third leading cause of cancer
mortality worldwide. Localized GC can be cured with surgery, but most patients present with …

[HTML][HTML] Challenges of diagnostic genomics in Latin America

RM Alvarez-Gomez… - Current Opinion in …, 2021 - Elsevier
Cancer genome sequencing methods have now become essential for diagnostic purposes,
for devising treatment strategies, and for monitoring disease regression and progression …

Her2-positive and microsatellite instability status in gastric cancer—clinicopathological implications

A Bermúdez, I Arranz-Salas, S Mercado… - Diagnostics, 2021 - mdpi.com
Gastric cancer (GC) is one of the leading causes of cancer-related death. The combination
of new molecular classifications with clinicopathological data could contribute to the …

High proportion of potential candidates for immunotherapy in a chilean cohort of gastric cancer patients: Results of the FORCE1 study

M Cordova-Delgado, MP Pinto, IN Retamal… - Cancers, 2019 - mdpi.com
Gastric cancer (GC) is a heterogeneous disease. This heterogeneity applies not only to
morphological and phenotypic features but also to geographical variations in incidence and …

A case-control study of a combination of single nucleotide polymorphisms and clinical parameters to predict clinically relevant toxicity associated with fluoropyrimidine …

M Cordova-Delgado, ML Bravo, E Cumsille, CN Hill… - BMC cancer, 2021 - Springer
Background Fluoropyrimidine plus platinum chemotherapy remains the standard first line
treatment for gastric cancer (GC). Guidelines exist for the clinical interpretation of four DPYD …

A molecular stratification of chilean gastric cancer patients with potential clinical applicability

MP Pinto, M Córdova-Delgado, IN Retamal… - Cancers, 2020 - mdpi.com
Gastric cancer (GC) is a complex and heterogeneous disease. In recent decades, The
Cancer Genome Atlas (TCGA) and the Asian Cancer Research Group (ACRG) defined GC …

[HTML][HTML] Mutational landscape of gastric adenocarcinoma in Latin America: A genetic approach for precision medicine

D Cerrato-Izaguirre, YI Chirino, CM García-Cuellar… - Genes & …, 2022 - Elsevier
Latin-America (LATAM) is the second region in gastric cancer incidence; gastric
adenocarcinoma (GA) represents 95% of all cases. We provide a mutational landscape of …

Copy number alterations and epithelial-mesenchymal transition genes in diffuse and intestinal gastric cancers in Mexican patients

V Larios-Serrato… - Molecular …, 2022 - spandidos-publications.com
Gastric cancer (GC) is a common malignancy with the highest mortality rate among diseases
of the digestive system, worldwide. The present study of GC alterations is crucial to the …

[HTML][HTML] Planificación sanitaria a partir de los datos ómicos:¿ es posible esta idea para Chile?

JA Ríos, K Marcelain, F Plaza-Parrochia… - Revista médica de …, 2021 - SciELO Chile
Planificación sanitaria a partir de los datos ómicos: ¿es posible esta idea para Chile?
SciELO - Scientific Electronic Library Online vol.149 número11 Impacto social de la …