Malaria during pregnancy
M Fried, PE Duffy - Cold Spring Harbor …, 2017 - perspectivesinmedicine.cshlp.org
One hundred and twenty-five million women in malaria-endemic areas become pregnant
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …
PfEMP1–a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis
L Hviid, ATR Jensen - Advances in parasitology, 2015 - Elsevier
Plasmodium falciparum causes the most severe form of malaria and is responsible for
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …
First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria
B Mordmüller, M Sulyok, D Egger-Adam… - Clinical Infectious …, 2019 - academic.oup.com
Background Malaria in pregnancy has major impacts on mother and child health. To
complement existing interventions, such as intermittent preventive treatment and use of …
complement existing interventions, such as intermittent preventive treatment and use of …
Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
MD Larsen, M Lopez-Perez, EK Dickson… - Nature …, 2021 - nature.com
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
[HTML][HTML] Malaria in pregnancy: linking immunity and pathogenesis to prevention
SJ Rogerson, V Mwapasa… - Defining and Defeating …, 2007 - ncbi.nlm.nih.gov
Pregnant women are susceptible to malaria during pregnancy. Plasmodium falciparum,
which sequesters in the placenta, causes the greatest disease, contributing significantly to …
which sequesters in the placenta, causes the greatest disease, contributing significantly to …
Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA
Pregnancy-associated malaria (PAM) is a serious consequence of sequestration of
Plasmodium falciparum-parasitized erythrocytes (PE) in the placenta through adhesion to …
Plasmodium falciparum-parasitized erythrocytes (PE) in the placenta through adhesion to …
A review of human vaccine research and development: malaria
MP Girard, ZH Reed, M Friede, MP Kieny - Vaccine, 2007 - Elsevier
The last several years have seen significant progress in the development of vaccines
against malaria. Most recently, proof-of-concept of vaccine-induced protection from malaria …
against malaria. Most recently, proof-of-concept of vaccine-induced protection from malaria …
Placental malaria: a new insight into the pathophysiology
L Sharma, G Shukla - Frontiers in medicine, 2017 - frontiersin.org
Malaria in pregnancy poses a great health risk to mother and her fetus and results into
complications, such as abortion, still birth, intra uterine growth retardation, and low birth …
complications, such as abortion, still birth, intra uterine growth retardation, and low birth …
[HTML][HTML] Protective antibodies against placental malaria and poor outcomes during pregnancy, Benin
NT Ndam, L Denoeud-Ndam… - Emerging infectious …, 2015 - ncbi.nlm.nih.gov
Placental malaria is caused by Plasmodium falciparum–infected erythrocytes that bind to
placental tissue. Binding is mediated by VAR2CSA, a parasite antigen coded by the var …
placental tissue. Binding is mediated by VAR2CSA, a parasite antigen coded by the var …
Pregnancy-specific malarial immunity and risk of malaria in pregnancy and adverse birth outcomes: a systematic review
Background In endemic areas, pregnant women are highly susceptible to Plasmodium
falciparum malaria characterized by the accumulation of parasitized red blood cells (pRBC) …
falciparum malaria characterized by the accumulation of parasitized red blood cells (pRBC) …