The plasminogen activator (PA) system is an extracellular proteolytic enzyme system
associated with various physiological and pathophysiological processes. A large body of …

Nanotechnology applications in medicine, termed as nanomedicine, have introduced a
number of nanoparticles of variable chemistry and architecture for cancer imaging and …

The urokinase‐type plasminogen activator (u‐PA) system consists of the serine proteinases
plasmin and u‐PA; the serpin inhibitors α2‐anti‐plasmin, PAI‐1 and PAI‐2; and the u‐PA …

Urokinase-type plasminogen activator receptor (uPAR) is an attractive target for the
treatment of cancer, because it is expressed at low levels in healthy tissues but at high levels …

The antigen levels of components of the urokinase-type plasminogen activator (uPA) system
of plasminogen activation are correlated with prognosis in several types of cancers …

Postlactational involution of the mammary gland is characterized by two distinct
physiological events: apoptosis of the secretory, epithelial cells undergoing programmed …

The cellular receptor for human urokinase-type plasminogen activator (u-PAR) is shown by
several independent criteria to be a true member of a family of integral membrane proteins …

The study of tumor biology has, in recent years, focused on the abnormal regulation of
growth control an neoplastic cells and on the genes that control tumor cell proliferation …

Any perturbation of the blood brain barrier, whether from changes in cell physiology or from
direct injury, may result in microvascular dysfunction and disease. We examined, at the …

Invasive bacterial pathogens intervene at various stages and by various mechanisms with
the mammalian plasminogen/plasmin system. A vast number of pathogens express plasmin …