The sirtuin family in health and disease

QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

NF‐κB signaling in inflammation and cancer

T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …

Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases

A El Midaoui, I Ghzaiel, D Vervandier-Fasseur, M Ksila… - Nutrients, 2022 - mdpi.com
Saffron (Crocus sativus L.) is a medicinal plant, originally cultivated in the East and Middle
East, and later in some Mediterranean countries. Saffron is obtained from the stigmas of the …

[HTML][HTML] An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin

S Bastani, V Vahedian, M Rashidi, A Mir… - Biomedicine & …, 2022 - Elsevier
Crocin, an active ingredient derived from saffron, is one of the herbal components that has
recently been considered by researchers. Crocin has been shown to have many anti …

Crocin: Functional characteristics, extraction, food applications and efficacy against brain related disorders

A Ali, L Yu, S Kousar, W Khalid, Z Maqbool… - Frontiers in …, 2022 - frontiersin.org
Crocin is a bioactive compound that naturally occurs in some medicinal plants, especially
saffron and gardenia fruit. Different conventional and novel methods are used for its …

A review of therapeutic impacts of saffron (Crocus sativus L.) and its constituents

F Anaeigoudari, A Anaeigoudari… - Physiological …, 2023 - Wiley Online Library
Application of herbal medicines in the treatment of diseases is in the center of attention of
medical scientific societies. Saffron (Cricus sativus L.) is a medicinal plant belonging to the …

Crocin molecular signaling pathways at a glance: A comprehensive review

M Boozari, H Hosseinzadeh - Phytotherapy Research, 2022 - Wiley Online Library
Crocin is a hydrophilic carotenoid that is synthesized in the flowers of the Crocus genus.
Numerous in vitro and in vivo research projects have been published about the biological …

[HTML][HTML] Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence

SF Omidkhoda, H Hosseinzadeh - Iranian Journal of Basic Medical …, 2022 - ncbi.nlm.nih.gov
Saffron, the stigmas of Crocus sativus L., has been mentioned extensively in the traditional
reference texts as a herbal medicine. Many clinical trials have been conducted on this …

The genus Crocus L.: A review of ethnobotanical uses, phytochemistry and pharmacology

L Mohtashami, MS Amiri, M Ramezani… - Industrial Crops and …, 2021 - Elsevier
Crocus L. is a genus of perennial plants in the family Iridaceae. Numerous research
regarding healing effects of Crocus spp. on human diseases are being published worldwide …

[HTML][HTML] Carotenoids in health as studied by omics-related endpoints

T Bohn, E Balbuena, H Ulus, M Iddir, G Wang… - Advances in …, 2023 - Elsevier
Carotenoids have been associated with risk reduction for several chronic diseases,
including the association of their dietary intake/circulating levels with reduced incidence of …