The role of genetic polymorphisms in diabetic retinopathy: Narrative review

E Sienkiewicz-Szłapka, E Fiedorowicz… - International Journal of …, 2023 - mdpi.com
Diabetic retinopathy (DR) is renowned as a leading cause of visual loss in working-age
populations with its etiopathology influenced by the disturbance of biochemical metabolic …

[HTML][HTML] Identification of prognostic biomarkers in colorectal cancer using a long non‑coding RNA‑mediated competitive endogenous RNA network

M He, Y Lin, Y Xu - Oncology letters, 2019 - spandidos-publications.com
Colorectal cancer (CRC) is a highly malignant gastrointestinal tumor accompanied by poor
prognosis. Long non‑coding RNA (lncRNA) plays an important role in the progression and …

Identification of drug-like molecules targeting the ATPase activity of dynamin-like EHD4

S Mohd, A Oder, E Specker, M Neuenschwander… - Plos one, 2024 - journals.plos.org
Eps15 (epidermal growth factor receptor pathway substrate 15) homology domain-
containing proteins (EHDs) comprise a family of eukaryotic dynamin-related ATPases that …

Deficiency of G9a inhibits cell proliferation and activates autophagy via transcriptionally regulating c-Myc expression in glioblastoma

XX Ke, R Zhang, X Zhong, L Zhang… - Frontiers in Cell and …, 2020 - frontiersin.org
Glioblastoma is an aggressive and difficult to treat cancer. Recent data have emerged
implicating that histone modification level may play a crucial role in glioma genesis. The …

[HTML][HTML] Identification of key genes by integrating DNA methylation and next-generation transcriptome sequencing for esophageal squamous cell carcinoma

Y Chen, LD Liao, ZY Wu, Q Yang, JC Guo… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Aberrant DNA methylation leads to abnormal gene expression, making it a significant
regulator in the progression of cancer and leading to the requirement for integration of gene …

[HTML][HTML] EHD3 promotes gastric cancer progression via Wnt/β-catenin/EMT pathway and associates with clinical prognosis and immune infiltration

J Yu, Y Yan, C Hua, H Song - American Journal of Cancer …, 2023 - ncbi.nlm.nih.gov
Gastric cancer (GC) shows high levels of heterogeneity and predicts a poor prognosis. The
expressions of EHD3 are found to be misregulated in a number of tumors. However, the …

EHD1 confers resistance to cisplatin in non-small cell lung cancer by regulating intracellular cisplatin concentrations

J Gao, Q Meng, Y Zhao, X Chen, L Cai - BMC cancer, 2016 - Springer
Background Non-small cell lung cancer (NSCLC) is one of the most aggressive types of
cancer. However, resistance to cisplatin (CDDP) remains a major challenge in NSCLC …

EHD1 and RUSC2 control basal epidermal growth factor receptor cell surface expression and recycling

EC Tom, I Mushtaq, BC Mohapatra… - … and cellular biology, 2020 - Am Soc Microbiol
Epidermal growth factor receptor (EGFR) is a prototype receptor tyrosine kinase and an
oncoprotein in many solid tumors. Cell surface display of EGFR is essential for cellular …

Eps15 homology domain-containing protein 3 regulates cardiac T-type Ca2+ channel targeting and function in the atria

J Curran, H Musa, CF Kline, MA Makara… - Journal of Biological …, 2015 - ASBMB
Proper trafficking of membrane-bound ion channels and transporters is requisite for normal
cardiac function. Endosome-based protein trafficking of membrane-bound ion channels and …

Development of cancer prognostic signature based on pan-cancer proteomics

W Huang, J Chen, W Weng, Y Xiang, H Shi… - …, 2020 - Taylor & Francis
Utilizing genomic data to predict cancer prognosis was insufficient. Proteomics can improve
our understanding of the etiology and progression of cancer and improve the assessment of …