Hypertension affects a significant proportion of the adult and aging population and
represents an important risk factor for vascular cognitive impairment and late-life dementia …

Dementia affects almost 50 million adults worldwide, and remains a major cause of death
and disability. Hypertension is a leading risk factor for dementia, including Alzheimer …

Abstract Background The triglyceride-glucose (TyG) index is a marker of insulin resistance
(IR) and has been associated with various metabolic syndromes, cardiovascular diseases …

Previous studies have explored the associations of retinal vessel calibre, measured from
retinal photographs or fundus images using semi-automated computer programs, with …

Elevated blood pressure is a well-established risk factor for age-related cognitive decline.
Long linked to cognitive impairment on vascular bases, increasing evidence suggests a …

Hypertension is an important cause of cerebral small vessel disease, especially of white
matter hyperintensity (WMH). The ability of intensive blood pressure (BP) control in …

Hypertension in midlife contributes to cognitive decline and is a modifiable risk factor for
dementia. The relationship between late-life hypertension and dementia is less clear. We …

Background Cerebral small vessel disease (cSVD) is a major contributing factor to ischemic
stroke and dementia. However, the vascular pathologies of cSVD remain inconclusive. The …

Aims Dysregulated immune response contributes to inefficiency of treatment strategies to
control hypertension and reduce the risk of end-organ damage. Uncovering the immune …

Background Although white matter hyperintensities (WMH) volumetric assessment is now
customary in research studies, inconsistent WMH measures among homogenous …