Polysaccharide-based nanomedicines targeting lung cancer
A primary illness that accounts for a significant portion of fatalities worldwide is cancer.
Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer …
Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer …
Inhalation delivery of repurposed drugs for lung cancer: approaches, benefits and challenges
Lung cancer (LC) is one of the leading causes of mortality accounting for almost 25% of
cancer deaths throughout the world. The shortfall of affordable and effective first-line …
cancer deaths throughout the world. The shortfall of affordable and effective first-line …
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin
Background Chemodynamic therapy (CDT) relying on intracellular iron ions and H2O2 is a
promising therapeutic strategy due to its tumor selectivity, which is limited by the not enough …
promising therapeutic strategy due to its tumor selectivity, which is limited by the not enough …
A dihydroartemisinin‐loaded nanoreactor motivates anti‐cancer immunotherapy by synergy‐induced ferroptosis to activate Cgas/STING for reprogramming of …
LG Li, XX Yang, HZ Xu, TT Yu, QR Li… - Advanced …, 2023 - Wiley Online Library
Infiltration of tumor‐associated macrophages (TAM) characterized by an M2 phenotype is an
overriding feature in malignant tumors. Reprogramming TAM is the most cutting‐edge …
overriding feature in malignant tumors. Reprogramming TAM is the most cutting‐edge …
A hyaluronic acid functionalized self-nano-emulsifying drug delivery system (SNEDDS) for enhancement in ciprofloxacin targeted delivery against intracellular …
Ciprofloxacin (CIP), a potent anti-bacterial agent of the fluroquinolone family, shows poor
solubility and permeability, thus leading to the development of intracellular pathogens …
solubility and permeability, thus leading to the development of intracellular pathogens …
Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage
LG Li, XC Peng, TT Yu, HZ Xu, N Han… - Frontiers in …, 2022 - frontiersin.org
Lung cancer recruits tumor-associated macrophages (TAMs) massively, whose
predominantly pro-tumor M2 phenotype leads to immunosuppression. Dihydroartemisinin …
predominantly pro-tumor M2 phenotype leads to immunosuppression. Dihydroartemisinin …
An annexin V-FITC—propidium iodide-based method for detecting apoptosis in a non-small cell lung cancer cell line
Annexin V and propidium iodide staining is widely used for determining the cellular death
through apoptosis. In the presence of Ca 2+ ions, annexin V has a strong binding affinity for …
through apoptosis. In the presence of Ca 2+ ions, annexin V has a strong binding affinity for …
Perspectives and controversies regarding the use of natural products for the treatment of lung cancer
T Wen, L Song, S Hua - Cancer Medicine, 2021 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related mortality both in men and women and
accounts for 18.4% of all cancer‐related deaths. Although advanced therapy methods have …
accounts for 18.4% of all cancer‐related deaths. Although advanced therapy methods have …
Polymer-drug conjugate, a potential therapeutic to combat breast and lung cancer
S Alven, X Nqoro, B Buyana, BA Aderibigbe - Pharmaceutics, 2020 - mdpi.com
Cancer is a chronic disease that is responsible for the high death rate, globally. The
administration of anticancer drugs is one crucial approach that is employed for the treatment …
administration of anticancer drugs is one crucial approach that is employed for the treatment …
[HTML][HTML] Development of nanoscale drug delivery systems of dihydroartemisinin for cancer therapy: A review
Abstract Dihydroartemisinin (DHA), a first-line antimalarial drug, has demonstrated great
anticancer effects in many types of tumors, including liver cancer, glioblastoma, and …
anticancer effects in many types of tumors, including liver cancer, glioblastoma, and …