[68Ga]Ga-PSMA-11: The First FDA-Approved 68Ga-Radiopharmaceutical for PET Imaging of Prostate Cancer

U Hennrich, M Eder - Pharmaceuticals, 2021 - mdpi.com
For the positron emission tomography (PET) imaging of prostate cancer, radiotracers
targeting the prostate-specific membrane antigen (PSMA) are nowadays used in clinical …

Good practices for 68Ga radiopharmaceutical production

BJB Nelson, JD Andersson, F Wuest… - EJNMMI …, 2022 - Springer
Abstract Background The radiometal gallium-68 (68Ga) is increasingly used in diagnostic
positron emission tomography (PET), with 68Ga-labeled radiopharmaceuticals developed …

Intraindividual comparison of [68 Ga]-Ga-PSMA-11 and [18F]-F-PSMA-1007 in prostate cancer patients: a retrospective single-center analysis

S Hoberück, S Löck, A Borkowetz, U Sommer… - EJNMMI research, 2021 - Springer
Background The analysis aimed to compare the radiotracers [68 Ga]-Ga-PSMA-11 and [18
F]-F-PSMA-1007 intraindividually in terms of malignant lesions, mi (molecular-imaging) TNM …

Recent advances in radiometals for combined imaging and therapy in cancer

N Herrero Álvarez, D Bauer, J Hernández‐Gil… - …, 2021 - Wiley Online Library
Nuclear medicine is defined as the use of radionuclides for diagnostic and therapeutic
applications. The imaging modalities positron emission tomography (PET) and single …

Joint EANM, SNMMI and IAEA enabling guide: how to set up a theranostics centre

K Herrmann, L Giovanella, A Santos, J Gear… - European Journal of …, 2022 - Springer
The theranostics concept using the same target for both imaging and therapy dates back to
the middle of the last century, when radioactive iodine was first used to treat thyroid …

Cold Kit Labeling: The Future of 68Ga Radiopharmaceuticals?

N Lepareur - Frontiers in Medicine, 2022 - frontiersin.org
Over the last couple of decades, gallium-68 (68Ga) has gained a formidable interest for PET
molecular imaging of various conditions, from cancer to infection, through cardiac …

Clinically applicable cyclotron-produced gallium-68 gives high-yield radiolabeling of DOTA-based tracers

E Jussing, S Milton, E Samén, MM Moein, L Bylund… - Biomolecules, 2021 - mdpi.com
By using solid targets in medical cyclotrons, it is possible to produce large amounts of
68GaCl3. Purification of Ga3+ from metal ion impurities is a critical step, as these metals …

68Ga-labeled ODAP-Urea-based PSMA agents in prostate cancer: first-in-human imaging of an optimized agent

X Duan, Z Cao, H Zhu, C Liu, X Zhang, J Zhang… - European Journal of …, 2022 - Springer
Purpose Prostate-specific membrane antigen (PSMA) is a promising target for prostate
cancer imaging and therapy. The most commonly used scaffold incorporates a glutamate …

Diagnosis of glioblastoma by immuno-positron emission tomography

E Ruiz-López, J Calatayud-Pérez, I Castells-Yus… - Cancers, 2021 - mdpi.com
Simple Summary Neuroimaging has transformed the way brain tumors are diagnosed and
treated. Although different non-invasive modalities provide very helpful information, in some …

[HTML][HTML] Demystifying solid targets: Simple and rapid distribution-scale production of [68Ga] GaCl3 and [68Ga] Ga-PSMA-11

J Svedjehed, M Pärnaste, K Gagnon - Nuclear Medicine and Biology, 2022 - Elsevier
Background As the demand for 68 Ga continues to grow, there is increasing interest in
single-to-multi-Curie production quantities of both [68 Ga] GaCl 3 and tracers such as [68 …