Apoptosis Inhibitor 5: A Multifaceted Regulator of Cell Fate

H Abbas, DK Derkaoui, L Jeammet, E Adicéam… - Biomolecules, 2024 - mdpi.com
Apoptosis, or programmed cell death, is a fundamental process that maintains tissue
homeostasis, eliminates damaged or infected cells, and plays a crucial role in various …

Validation of AAC-11-derived peptide anti-tumor activity in a single graft sezary patient-derived xenograft mouse model

J Habault, N Thonnart, C Ram-Wolff, M Bagot… - Cells, 2022 - mdpi.com
Sézary syndrome (SS) is an aggressive cutaneous T cell lymphoma with poor prognosis
mainly characterized by the expansion of a tumor CD4+ T cell clone in both skin and blood …

Killing of Plasmodium Sporozoites by Basic Amphipathic α-Helical Fusion Peptides

MC Aguirre-Botero, E Aliprandini, A Gladston, O Pacios… - Microorganisms, 2024 - mdpi.com
Membranolytic molecules constitute the first line of innate immune defense against
pathogenic microorganisms. Plasmodium sporozoites are potentially exposed to these …

Poptosis or Peptide-Induced Transmembrane Pore Formation: A Novel Way to Kill Cancer Cells without Affecting Normal Cells

MR Pincus, M Silberstein, N Zohar, E Sarafraz-Yazdi… - Biomedicines, 2024 - mdpi.com
Recent advances in cancer treatment like personalized chemotherapy and immunotherapy
are aimed at tumors that meet certain specifications. In this review, we describe a new …