Background and objective Osteoarthritis (OA) is a highly prevalent, disabling disease
requiring chronic management that is associated with an enormous individual and societal …

Knee osteoarthritis (OA) is a common condition, prevalent in middle-agedness, associated
with chronic pain and impaired quality of life. Two interrelated biological processes fuel early …

Objective Obesity exacerbates pain and functional limitation in persons with knee
osteoarthritis (OA). In the Weight Loss and Exercise for Communities with Arthritis in North …

Objective Gabapentin can treat neuropathic pain syndromes and has increasingly been
prescribed to treat nociplastic pain. Some patients with knee osteoarthritis (OA) suffer from …

Objectives To assess the relation of obesity to opioid use in people with or at risk of knee
osteoarthritis (OA), and the extent to which this association is mediated by number of painful …

Background Tamoxifen (TAM) is recommended as the first-line strategy for men with
estrogen receptor (ER)-positive early breast cancer who are candidates for adjuvant …

Abstract Background and Aim: Osteoarthritis (OA) is a very common painful disease of the
musculoskeletal system. The limitation of the effectiveness of current analgesics had been …