Syndecans are a small family of four transmembrane proteoglycans in mammals. They have
similar structural organization, consisting of an N‐terminal ectodomain, single …

Heparin, a sulfated polysaccharide belonging to the family of glycosaminoglycans, has
numerous important biological activities, associated with its interaction with diverse proteins …

Fibroblast growth factors (FGFs) are small polypeptide growth factors, all of whom share in
common certain structural characteristics, and most of whom bind heparin avidly. Many …

Inorganic polyphosphate (Poly P) is a polymer of tens to hundreds of phosphate residues
linked by “high-energy” phosphoanhydride bonds as in ATP. Found in abundance in all cells …

Biological Roles of Fibroblast Growth Factor-2* | Endocrine Reviews | Oxford Academic
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FGF signaling plays a ubiquitous role in human biology as a regulator of embryonic
development, homeostasis and regenerative processes. In addition, aberrant FGF signaling …

Fibroblast growth factors (FGFs) comprise a large family of developmental and physiological
signaling molecules. All FGFs have a high affinity for the glycosaminoglycan heparin and for …

Abstract Adeno-associated virus 2 (AAV)-based vectors have gained attention as a
potentially useful alternative to the more commonly used retroviral and adenoviral vectors for …

Members of the fibroblast growth factor (FGF) family play pleiotropic roles in cellular and
metabolic homeostasis. During evolution, the ancestor FGF expands into multiple members …

Heparin, a sulfated polysaccharide, is a major clinical anticoagulant. It is exploited to
overcome the natural propensity for blood to clot. Surgical procedures often require …