Antidepressant drug sertraline against human cancer cells

D Duarte, N Vale - Biomolecules, 2022 - mdpi.com
The use of FDA-approved drugs for new indications represents a faster and more
economical way to find novel therapeutic agents for cancer therapy, compared to the …

Use of antidepressants in patients with depression and comorbid diabetes mellitus: a systematic review

S Roopan, ER Larsen - Acta neuropsychiatrica, 2017 - cambridge.org
ObjectiveDepression may be difficult to treat and with comorbid diabetes mellitus (DM) it is
an even bigger challenge. This article aims to evaluate antidepressants most suitable for …

The effects of exercise on anxiety and depression

SM Arent, AJ Walker, MA Arent - Handbook of sport psychology, 2020 - Wiley Online Library
Together, the stress‐related conditions of anxiety and depression represent the two most
common mental health disorders. This chapter provides an overview of the research …

Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression

S Pan, Y Tan, S Yao, Y Xin, X Yang, J Liu… - Acta Pharmacologica …, 2018 - nature.com
Depressive disorders are frequently managed with long-term use of antidepressant
medication. Fluoxetine (FLX) is the first selective serotonin reuptake inhibitor to be widely …

Effects of long-term sertraline treatment and depression on coronary artery atherosclerosis in premenopausal female primates

CA Shively, TC Register, SE Appt… - Psychosomatic …, 2015 - journals.lww.com
Objectives Major depressive disorder and coronary heart disease often co-occur in the same
individuals. Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed for …

Therapy management of metabolic disorder comorbidity with depression

H Luo, ZL Jiang, Y Ren - Frontiers in Psychology, 2021 - frontiersin.org
Depression is a common disease that seriously endangers the physical and mental health of
human beings, and it often coexists with other metabolic disorders such as diabetes and …

[HTML][HTML] Effect of laser acupuncture combined with a diet-exercise intervention on metabolic syndrome in post-menopausal women

HS El-Mekawy, AM ElDeeb, HO Ghareib - Journal of Advanced Research, 2015 - Elsevier
This study aimed to evaluate the effect of laser acupuncture combined with a diet-exercise
intervention on features of the metabolic syndrome (MetS). Twenty-eight obese post …

[HTML][HTML] Metabolic risk in depression and treatment with selective serotonin reuptake inhibitors: are the metabolic syndrome and an increase in cardiovascular risk …

M Chávez-Castillo, Á Ortega, M Nava, J Fuenmayor… - Vessel Plus, 2018 - oaepublish.com
Depression is one of the most common psychiatric disorders, and has become an epidemic
in modern medical practice; notorious for frequently co-occurring with multiple comorbidities …

The selective serotonin reuptake inhibitors, sertraline and paroxetine, improve islet beta‐cell mass and function in vitro

K Toczyska, N Haq, Z Lyu, G Bewick… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aims To investigate the effects of the selective serotonin reuptake inhibitors (SSRIs)
sertraline and paroxetine at therapeutically relevant concentrations on beta‐cell mass and …

The impact of treatment with selective serotonin reuptake inhibitors on primate cardiovascular disease, behavior, and neuroanatomy

CA Shively, M Silverstein-Metzler, J Justice… - Neuroscience & …, 2017 - Elsevier
Selective serotonin reuptake inhibitor (SSRI) use is ubiquitous because they are widely
prescribed for a number of disorders in addition to depression. Depression increases the …