Targeting the blood-brain barrier for the delivery of stroke therapies
A variety of neuroprotectants have shown promise in treating ischemic stroke, yet their
delivery to the brain remains a challenge. The endothelial cells lining the blood-brain barrier …
delivery to the brain remains a challenge. The endothelial cells lining the blood-brain barrier …
Brain‐derived neurotrophic factor and its potential therapeutic role in stroke comorbidities
W Liu, X Wang, M O'Connor, G Wang, F Han - Neural plasticity, 2020 - Wiley Online Library
With the rise in the aging global population, stroke comorbidities have become a serious
health threat and a tremendous economic burden on human society. Current therapeutic …
health threat and a tremendous economic burden on human society. Current therapeutic …
The role of BDNF in multiple sclerosis neuroinflammation
V Nociti, M Romozzi - International Journal of Molecular Sciences, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic, inflammatory, and degenerative disease of the central
nervous system (CNS). Inflammation is observed in all stages of MS, both within and around …
nervous system (CNS). Inflammation is observed in all stages of MS, both within and around …
Circulating brain-derived neurotrophic factor as a potential biomarker in stroke: a systematic review and meta-analysis
Background Stroke, an acute cerebrovascular event, is a leading cause of disability, placing
a significant psycho-socioeconomic burden worldwide. The adaptation and reorganization …
a significant psycho-socioeconomic burden worldwide. The adaptation and reorganization …
Serum BDNF levels in acute stroke: a systematic review and meta-analysis
E Karantali, D Kazis, V Papavasileiou, A Prevezianou… - Medicina, 2021 - mdpi.com
Background and objectives: Brain-derived neurotrophic factor (BDNF) is one of the most
studied neurotrophins. Low BDNF concentrations have been noted in patients with …
studied neurotrophins. Low BDNF concentrations have been noted in patients with …
Effects of virtual reality-based motor control training on inflammation, oxidative stress, neuroplasticity and upper limb motor function in patients with chronic stroke: a …
CY Huang, WC Chiang, YC Yeh, SC Fan, WH Yang… - BMC neurology, 2022 - Springer
Background Immersive virtual reality (VR)-based motor control training (VRT) is an
innovative approach to improve motor function in patients with stroke. Currently, outcome …
innovative approach to improve motor function in patients with stroke. Currently, outcome …
Neurovascular unit as a source of ischemic stroke biomarkers—limitations of experimental studies and perspectives for clinical application
A Steliga, P Kowiański, E Czuba, M Waśkow… - Translational stroke …, 2020 - Springer
Cerebral stroke, which is one of the most frequent causes of mortality and leading cause of
disability in developed countries, often leads to devastating and irreversible brain damage …
disability in developed countries, often leads to devastating and irreversible brain damage …
Cognitive rehabilitation improves ischemic stroke-induced cognitive impairment: role of growth factors
F Farokhi-Sisakht, M Farhoudi… - Journal of Stroke and …, 2019 - Elsevier
Cognitive dysfunction is the most common nonphysical impairment in the stroke survivors.
This impairment has a negative impact on patients' quality of life affects their daily living …
This impairment has a negative impact on patients' quality of life affects their daily living …
Promoting neuroregeneration after perinatal arterial ischemic stroke: neurotrophic factors and mesenchymal stem cells
N Wagenaar, CGM De Theije, LS De Vries… - Pediatric …, 2018 - nature.com
Newborns suffering from perinatal arterial ischemic stroke (PAIS) are at risk of
neurodevelopmental problems. Current treatment options for PAIS are limited and mainly …
neurodevelopmental problems. Current treatment options for PAIS are limited and mainly …
[HTML][HTML] Increased serum brain-derived neurotrophic factor with high-intensity interval training in stroke patients: a randomized controlled trial
CC Hsu, TC Fu, SC Huang, CPC Chen… - Annals of physical and …, 2021 - Elsevier
Background Physiological adaptations of stroke patients after high-intensity interval training
(HIIT) and moderate-intensity continuous training (MICT) remain unclear. Objective This …
(HIIT) and moderate-intensity continuous training (MICT) remain unclear. Objective This …