Treatment strategies against diabetes: Success so far and challenges ahead

R Khursheed, SK Singh, S Wadhwa, B Kapoor… - European journal of …, 2019 - Elsevier
The growing disease burden of diabetes mellitus is an important public health concern,
affecting over 400 million people globally. This epidemic, if not controlled in time, leads to …

A global perspective on the issue of access to insulin

D Beran, M Lazo-Porras, CM Mba, JC Mbanya - Diabetologia, 2021 - Springer
The discovery of insulin in 1921 changed the prognosis for people with type 1 diabetes. A
century later, availability and affordability of insulin remain a challenge in many parts of the …

Scale‐up economics for cultured meat

D Humbird - Biotechnology and Bioengineering, 2021 - Wiley Online Library
This analysis examines the potential of “cultured meat” products made from edible animal
cell culture to measurably displace the global consumption of conventional meat …

IoMT-based wearable body sensors network healthcare monitoring system

EA Adeniyi, RO Ogundokun, JB Awotunde - IoT in healthcare and ambient …, 2021 - Springer
Abstract The Internet of Medical Things (IoMT) is the gathering and implementation of
healthcare tools connected to public healthcare technology infrastructure via Internet-based …

Advanced glycation end products: potential mechanism and therapeutic target in cardiovascular complications under diabetes

P Yang, J Feng, Q Peng, X Liu… - Oxidative Medicine and …, 2019 - Wiley Online Library
The occurrence and development of cardiovascular complications are predominantly
responsible for the increased morbidity and mortality observed in patients with diabetes …

Efficacy and safety of imeglimin add‐on to insulin monotherapy in Japanese patients with type 2 diabetes (TIMES 3): A randomized, double‐blind, placebo‐controlled …

C Reilhac, J Dubourg, C Thang… - Diabetes, Obesity …, 2022 - Wiley Online Library
Aims To evaluate the efficacy and safety of imeglimin for up to 52 weeks as combination
therapy with insulin in Japanese patients with type 2 diabetes. Materials and Methods This …

Technology in the management of type 2 diabetes: present status and future prospects

A Daly, R Hovorka - Diabetes, Obesity and Metabolism, 2021 - Wiley Online Library
The growing incidence of type 2 diabetes (T2D) is a significant health concern, representing
90% of diabetes cases worldwide. As the disease progresses, resultant insulin deficiency …

A fluorescence sandwich immunoassay for the real-time continuous detection of glucose and insulin in live animals

M Poudineh, CL Maikawa, EY Ma, J Pan… - Nature biomedical …, 2021 - nature.com
Biosensors that continuously measure circulating biomolecules in real time could provide
insights into the health status of patients and their response to therapeutics. But biosensors …

[HTML][HTML] The type 2 diabetes 'modern preventable pandemic'and replicable lessons from the COVID-19 crisis

ME Singer, KA Dorrance, MM Oxenreiter… - Preventive Medicine …, 2022 - Elsevier
To frame the substantial prevalence of type 2 diabetes (T2D) as a 'Modern Preventable
Pandemic'(MPP) and present certain replicable policy lessons from the COVID-19 crisis to …

The chemical synthesis of insulin: an enduring challenge

JA Karas, JD Wade, MA Hossain - Chemical reviews, 2021 - ACS Publications
The pancreatic peptide hormone insulin, first discovered exactly 100 years ago, is essential
for glycemic control and is used as a therapeutic for the treatment of type 1 and, increasingly …