Exosomes, which are small vesicles enclosed by a lipid bilayer and released by many cell
types, are widely dispersed and have garnered increased attention in the field of …

Research has advanced considerably since the first clinical trial of human mesenchymal
stem cells (MSCs) in the early 1990s. During this period, our understanding of MSC biology …

Extracellular vesicles (EVs) from cultured cells or bodily fluids have been demonstrated to
show therapeutic value following myocardial infarction. However, challenges in donor …

Background Cardiovascular disease (CVD) has been the leading cause of death worldwide
for many years. In recent years, exosomes have gained extensive attention in the …

Calorie restriction (CR) and fasting affect lifespan, disease susceptibility and response to
acute injury across multiple animal models, including ischaemic injuries such as myocardial …

Cell therapy has significant therapeutic potential but is often limited by poor donor cell
retention and viability at the host implantation site. Biomaterials can improve cell retention by …

Compared with stem cells, exosomes as a kind of nanoscale carriers intrinsically loaded
with diverse bioactive molecules, which had the advantages of high safety, small size, and …

Bioreactors are growing in popularity among network engineers. Bioreactors are generally
chambers used for cell culture processes with predetermined parameters. Pivot is a …

Encapsulated cell therapy (ECT) shows significant potential for treating neurodegenerative
disorders including Alzheimer's and Parkinson's, which currently lack curative medicines …

This study investigates the characteristics of cardiac mesenchymal stem cell-like cells
(CMSCLCs) isolated from the right atrial appendage of human donors with ischemia and a …