Polymeric nanostructured materials for biomedical applications

Z Tang, C He, H Tian, J Ding, BS Hsiao, B Chu… - Progress in Polymer …, 2016 - Elsevier
Polymeric nanostructured materials (PNMs), which are polymeric materials in nanoscale or
polymer composites containing nanomaterials, have become increasingly useful for …

Recent advances of chitosan nanoparticles as drug carriers

JJ Wang, ZW Zeng, RZ Xiao, T Xie… - International journal …, 2011 - Taylor & Francis
Chitosan nanoparticles are good drug carriers because of their good biocompatibility and
biodegradability, and can be readily modified. As a new drug delivery system, they have …

Methods for the preparation and manufacture of polymeric nanoparticles

C Vauthier, K Bouchemal - Pharmaceutical research, 2009 - Springer
This review summarizes the different methods of preparation of polymer nanoparticles
including nanospheres and nanocapsules. The first part summarizes the basic principle of …

Polysaccharide-decorated nanoparticles

C Lemarchand, R Gref, P Couvreur - European Journal of Pharmaceutics …, 2004 - Elsevier
Surface modified colloidal carriers such as nanoparticles are able to modulate the
biodistribution of the loaded drug when given intravenously, but also to control the …

Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin

M Juenet, R Aid-Launais, B Li, A Berger, J Aerts… - Biomaterials, 2018 - Elsevier
Injection of recombinant tissue plasminogen activator (rt-PA) is the standard drug treatment
for thrombolysis. However, rt-PA shows risk of hemorrhages and limited efficiency even at …

Mucoadhesion mechanism of chitosan and thiolated chitosan-poly (isobutyl cyanoacrylate) core-shell nanoparticles

I Bravo-Osuna, C Vauthier, A Farabollini, GF Palmieri… - Biomaterials, 2007 - Elsevier
The study is focused on the evaluation of the potential bioadhesive behaviour of chitosan
and thiolated chitosan (chitosan-TBA)-coated poly (isobutyl cyanoacrylates)(PIBCA) …

Polysaccharide‐block‐polypeptide Copolymer Vesicles: Towards Synthetic Viral Capsids

C Schatz, S Louguet, JF Le Meins… - Angewandte Chemie …, 2009 - Wiley Online Library
Natural inspiration: Amphiphilic polysaccharide‐block‐polypeptide copolymers were
synthesized by click chemistry from dextran end‐functionalized with an alkyne group and …

Synthetic polymeric nanoparticles by nanoprecipitation

S Hornig, T Heinze, CR Becer… - Journal of materials …, 2009 - pubs.rsc.org
Nanoprecipitation is applied for the first time as a general concept for manufacturing
nanoparticles of versatile hydrophobic polymer classes. As a result, polymer molecules self …

Drug delivery to resistant tumors: the potential of poly (alkyl cyanoacrylate) nanoparticles

C Vauthier, C Dubernet, C Chauvierre, I Brigger… - Journal of Controlled …, 2003 - Elsevier
Simultaneous cellular resistance to multiple lipophilic drugs represents a major problem in
cancer chemotherapy. This drug resistance may appear clinically either as a lack of tumor …

Purification processes of polymeric nanoparticles: How to improve their clinical translation?

SF Tehrani, P Bharadwaj, JL Chain… - Journal of Controlled …, 2023 - Elsevier
Polymeric nanoparticles, as revolutionary nanomedicines, have offered a new class of
diagnostic and therapeutic solutions for a multitude of diseases. With its immense potential …