Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical disease
that affects millions of people mainly in Latin America. To establish a life-long infection, T …

The surface of the protozoan parasite Trypanosoma cruzi is covered in mucins, which
contribute to parasite protection and to the establishment of a persistent infection. Their …

Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune
response in a very complex and flowery manner. The history of host-parasite co-evolution …

A novel large multigene family was recently identified in the human pathogen Trypanosoma
cruzi, causative agent of Chagas disease, and corresponds to∼ 6% of the parasite diploid …

Many important pathogen-host interactions rely on highly specific carbohydrate binding
events. In the case of the protozoan Trypanosoma cruzi, the causative agent of Chagas …

The protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a
highly debilitating human pathology that affects millions of people in the Americas. The …

Background Trypanosoma rangeli is a hemoflagellate protozoan parasite infecting humans
and other wild and domestic mammals across Central and South America. It does not cause …

The Trypanosoma cruzi trypomastigote membrane provides a major protective role against
mammalian host-derived defense mechanisms while allowing the parasite to interact with …

T rypanosoma cruzi trans‐sialidase (TS) was identified three decades ago. TS catalyses a
trans‐glycosylation reaction, transferring SA from sialylated donors to the terminal galactose …

Chagas' disease, caused by Trypanosoma cruzi, affects about 18 million people in Latin
America, and no effective treatment is available to date. To acquire sialic acid from the host …