WNT4 regulates cellular metabolism via intracellular activity at the mitochondria in breast and gynecologic cancers

JL Sottnik, MT Shackleford, SK Robinson… - Cancer Research …, 2024 - AACR
Wnt ligand WNT4 is critical in female reproductive tissue development, with WNT4
dysregulation linked to related pathologies including breast cancer (invasive lobular …

Unlocking the mysteries of lobular breast cancer biology needs the right combination of preclinical models

S Bahnassy, MJ Sikora, RB Riggins - Molecular Cancer Research, 2022 - AACR
Preclinical model systems are essential research tools that help us understand the biology
of invasive lobular carcinoma of the breast (ILC). The number of well-established ILC …

O potencial uso do riluzole no tratamento do câncer: revisão sistemática

C Valero, PM Bezerra, MM Perez… - Saúde e meio ambiente …, 2023 - periodicos.unc.br
O riluzole tem sido usado para o tratamento da Esclerose Lateral Amiotrófica (ELA). Estudos
experimentais têm mostrado inibição do crescimento tumoral com riluzole. O objetivo desta …