Emerging fungal infections: new patients, new patterns, and new pathogens

DZP Friedman, IS Schwartz - Journal of Fungi, 2019 - mdpi.com
The landscape of clinical mycology is constantly changing. New therapies for malignant and
autoimmune diseases have led to new risk factors for unusual mycoses. Invasive …

Invasive fusariosis

M Nucci, E Anaissie - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Invasive fusariosis is a serious invasive fungal disease, affecting immunocompetent and,
more frequently, immunocompromised patients. Localized disease is the typical clinical form …

Human fusariosis: An emerging infection that is difficult to treat

BG Batista, MA Chaves, P Reginatto… - Revista da Sociedade …, 2020 - SciELO Brasil
Fusarium spp. has been associated with a broad spectrum of emerging infections
collectively termed fusariosis. This review includes articles published between 2005 and …

Therapeutic drug monitoring of posaconazole: an update

BGJ Dekkers, M Bakker, KCM van der Elst… - Current fungal infection …, 2016 - Springer
Posaconazole is a second-generation triazole agent with a potent and broad antifungal
activity. In addition to the oral suspension, a delayed-release tablet and intravenous …

Invasive fusariosis in patients with hematologic diseases

M Nucci, G Barreiros, T Akiti, E Anaissie, SA Nouér - Journal of Fungi, 2021 - mdpi.com
Fusarium species are filamentous fungi widely encountered in nature, and may cause
invasive disease in patients with hematologic conditions. Patients at higher risk are those …

Consensus guidelines for the diagnosis and management of invasive fungal disease due to moulds other than Aspergillus in the haematology/oncology setting, 2021

O Bupha‐Intr, C Butters, G Reynolds… - Internal Medicine …, 2021 - Wiley Online Library
Invasive fungal disease (IFD) due to moulds other than Aspergillus is a significant cause of
mortality in patients with malignancies or post haemopoietic stem cell transplantation. The …

International evaluation of MIC distributions and epidemiological cutoff value (ECV) definitions for Fusarium species identified by molecular methods for the CLSI broth …

A Espinel-Ingroff, AL Colombo, S Cordoba… - Antimicrobial agents …, 2016 - Am Soc Microbiol
The CLSI epidemiological cutoff values (ECVs) of antifungal agents are available for various
Candida spp., Aspergillus spp., and the Mucorales. However, those categorical endpoints …

Specific antifungal susceptibility profiles of opportunists in the Fusarium fujikuroi complex

AMS Al-Hatmi, AD van Diepeningen… - Journal of …, 2015 - academic.oup.com
Objectives The aim of the present study was to evaluate and assess the in vitro activity of
eight drugs, including the new azole isavuconazole, against 81 strains representing 13 …

A practical workflow for the identification of Aspergillus, Fusarium, Mucorales by MALDI-TOF MS: database, medium, and incubation optimization

KR Barker, JV Kus, AC Normand… - Journal of Clinical …, 2022 - Am Soc Microbiol
There is an increasing body of literature on the utility of MALDI-TOF MS in the identification
of filamentous fungi. However, the process still lacks standardization. In this study, we …

Broad spectrum triazoles for invasive mould infections in adults: Which drug and when?

JD Jenks, SR Mehta, M Hoenigl - Medical mycology, 2019 - academic.oup.com
Invasive mould infections are an increasing cause of morbidity and mortality globally, mainly
due to increasing numbers of immunocompromised individuals at risk for fungal infections …