Congenital hypothyroidism (CH) occurs in approximately 1: 2,000 to 1: 4,000 newborns. The
clinical manifestations are often subtle or not present at birth. This likely is due to trans …

Unrecognized congenital hypothyroidism leads to mental retardation. Newborn screening
and thyroid therapy started within 2 weeks of age can normalize cognitive development. The …

Thyroid hormone has important effects on almost every organ system and plays a crucial
role in normal growth and neurologic development. Congenital hypothyroidism affects …

Several reviews and meta-analyses have examined the effects of iodine on mental
development. None focused on young children, so they were incomplete in summarizing the …

Congenital hypothyroidism is the most common neonatal metabolic disorder and results in
severe neurodevelopmental impairment and infertility if untreated. Congenital …

Background There is increasing evidence in humans and in experimental animals for a
relationship between exposure to specific environmental chemicals and perturbations in …

The adequate functioning of both the maternal and fetal thyroid glands play an important
role to ensure that the fetal neuropsycho-intellectual development progresses normally …

OBJECTIVES: To compare neurodevelopmental outcomes in severe and moderate
congenital hypothyroidism (CH) among 3 different initial L-thyroxine doses and to examine …

This Technical Report was retired June 2015. Newborn screening fact sheets were last
revised in 1996 by the American Academy of Pediatrics Committee on Genetics. This …

Objective. To describe intellectual, motor, and school-associated outcome in young adults
with early treated congenital hypothyroidism (CH) and to study the association between long …