Long non-coding RNA XIST: a novel oncogene in multiple cancers
J Yang, M Qi, X Fei, X Wang, K Wang - Molecular Medicine, 2021 - Springer
Long non-coding RNA (lncRNA) X-inactive specific transcript (XIST) is an important lncRNA
derived from the XIST gene in mammals. XIST is abnormally expressed in numerous tumors …
derived from the XIST gene in mammals. XIST is abnormally expressed in numerous tumors …
Epigenetic aberrations in human pluripotent stem cells
S Bar, N Benvenisty - The EMBO journal, 2019 - embopress.org
Human pluripotent stem cells (hPSCs) are being increasingly utilized worldwide in
investigating human development, and modeling and discovering therapies for a wide range …
investigating human development, and modeling and discovering therapies for a wide range …
CRISPR-assisted detection of RNA–protein interactions in living cells
We have developed CRISPR-assisted RNA–protein interaction detection method (CARPID),
which leverages CRISPR–CasRx-based RNA targeting and proximity labeling to identify …
which leverages CRISPR–CasRx-based RNA targeting and proximity labeling to identify …
Characters, functions and clinical perspectives of long non-coding RNAs
R Wu, Y Su, H Wu, Y Dai, M Zhao, Q Lu - Molecular genetics and …, 2016 - Springer
It is well established that most of the human genome and those of other mammals and plants
are transcribed into RNA without protein-coding capacity, which we define as non-coding …
are transcribed into RNA without protein-coding capacity, which we define as non-coding …
Stepwise de novo establishment of inactive X chromosome architecture in early development
X chromosome inactivation triggers a dramatic reprogramming of transcription and
chromosome architecture. However, how the chromatin organization of inactive X …
chromosome architecture. However, how the chromatin organization of inactive X …
[HTML][HTML] Deciphering the roles of lncRNAs in breast development and disease
JLC Richard, PJA Eichhorn - Oncotarget, 2018 - ncbi.nlm.nih.gov
Breast cancer is the second leading cause of cancer related deaths in women. It is therefore
important to understand the mechanisms underlying breast cancer development as well as …
important to understand the mechanisms underlying breast cancer development as well as …
LncRNA XIST facilitates cell growth, migration and invasion via modulating H3 histone methylation of DKK1 in neuroblastoma
J Zhang, WY Li, Y Yang, LZ Yan, SY Zhang, J He… - Cell Cycle, 2019 - Taylor & Francis
Long non-coding RNAs (lncRNAs) have been confirmed to be aberrantly expressed and
involved in the progression of neuroblastoma. This study aimed to explore the expression …
involved in the progression of neuroblastoma. This study aimed to explore the expression …
Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome
N Yamada, Y Hasegawa, M Yue, T Hamada… - PLoS …, 2015 - journals.plos.org
To equalize X-linked gene dosage between the sexes in mammalian females, Xist RNA
inactivates one of the two X-chromosomes. Here, we report the crucial function of Xist exon 7 …
inactivates one of the two X-chromosomes. Here, we report the crucial function of Xist exon 7 …
Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression
M Yue, A Ogawa, N Yamada, JL Charles Richard… - PLoS …, 2017 - journals.plos.org
Long non-coding RNA Xist plays a crucial role in establishing and maintaining X-
chromosome inactivation (XCI) which is a paradigm of long non-coding RNA-mediated gene …
chromosome inactivation (XCI) which is a paradigm of long non-coding RNA-mediated gene …
Initiation of X chromosome inactivation during bovine embryo development
B Yu, HTA van Tol, TAE Stout, BAJ Roelen - Cells, 2020 - mdpi.com
X-chromosome inactivation (XCI) is a developmental process that aims to equalize the
dosage of X-linked gene products between XY males and XX females in eutherian …
dosage of X-linked gene products between XY males and XX females in eutherian …