Electrochemical late-stage functionalization

Y Wang, S Dana, H Long, Y Xu, Y Li… - Chemical …, 2023 - ACS Publications
Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or
diversification of novel molecular entities with improved physicochemical or biological …

Radical Carboxylative Cyclizations and Carboxylations with CO2

JH Ye, T Ju, H Huang, LL Liao… - Accounts of Chemical …, 2021 - ACS Publications
Conspectus Carbon dioxide (CO2) is not only a greenhouse gas and a common waste
product but also an inexpensive, readily available, and renewable carbon resource. It is an …

Visible-light photocatalytic di- and hydro-carboxylation of unactivated alkenes with CO2

L Song, W Wang, JP Yue, YX Jiang, MK Wei… - Nature Catalysis, 2022 - nature.com
High value utilization of carbon dioxide (CO2) has attracted worldwide attention for decades.
Catalytic carboxylation of alkenes with CO2 to synthesize valuable carboxylic acids and …

Electrochemical Ring-Opening Dicarboxylation of Strained Carbon–Carbon Single Bonds with CO2: Facile Synthesis of Diacids and Derivatization into Polyesters

LL Liao, ZH Wang, KG Cao, GQ Sun… - Journal of the …, 2022 - ACS Publications
Diacids are important monomers in the polymer industry to construct valuable materials.
Dicarboxylation of unsaturated bonds, such as alkenes and alkynes, with CO2 has been …

[HTML][HTML] Recent progress in cathodic reduction-enabled organic electrosynthesis: Trends, challenges, and opportunities

B Huang, Z Sun, G Sun - eScience, 2022 - Elsevier
Compared with general redox chemistry, electrochemistry using the electron as a potent,
controllable, yet traceless alternative to chemical oxidants/reductants usually offers more …

Electroreductive Dicarboxylation of Unactivated Skipped Dienes with CO2

W Zhang, LL Liao, L Li, Y Liu, LF Dai… - Angewandte Chemie …, 2023 - Wiley Online Library
Carboxylation of easily available alkenes with CO2 is highly important to afford value‐added
carboxylic acids. Although dicarboxylation of activated alkenes, especially 1, 3‐dienes, has …

Electrocarboxylation of Aryl Epoxides with CO2 for the Facile and Selective Synthesis of β‐Hydroxy Acids

Y Wang, S Tang, G Yang, S Wang… - Angewandte Chemie …, 2022 - Wiley Online Library
Herein, an efficient and facile approach to valuable β‐hydroxy acid derivatives from readily
available aryl epoxides and CO2 with high chemo‐and regioselectivity under mild and …

Site‐Selective Electrochemical C−H Carboxylation of Arenes with CO2

Z Zhao, Y Liu, S Wang, S Tang, D Ma, Z Zhu… - Angewandte …, 2023 - Wiley Online Library
Herein, a direct, metal‐free, and site‐selective electrochemical C− H carboxylation of arenes
by reductive activation using CO2 as the economic and abundant carboxylic source was …

Electrochemical dearomative dicarboxylation of heterocycles with highly negative reduction potentials

Y You, W Kanna, H Takano, H Hayashi… - Journal of the …, 2022 - ACS Publications
The dearomative dicarboxylation of stable heteroaromatics using CO2 is highly challenging
but represents a very powerful method for producing synthetically useful dicarboxylic acids …

Radical hydrocarboxylation of unactivated alkenes via photocatalytic formate activation

SN Alektiar, J Han, Y Dang, CZ Rubel… - Journal of the …, 2023 - ACS Publications
Herein we disclose a strategy to promote the hydrocarboxylation of unactivated alkenes
using photochemical activation of formate salts. We illustrate that an alternative initiation …