Hepatocarcinoma is one of the most prevalent gastroenterological cancers in the world with
less effective therapy. As an oncofetal antigen and diagnostic marker for liver cancer, alpha …

Fully effective vaccines for complex infections must elicit a diverse repertoire of antibodies
(humoral immunity) and CD8+ T-cell responses (cellular immunity). Here, we present a …

Oncolytic viruses are naturally occurring or genetically engineered viruses that can replicate
preferentially in tumor cells and inhibit tumor growth. These viruses have been considered …

Non–antigen-specific stimulatory cancer immunotherapies are commonly complicated by off-
target effects. Antigen-specific immunotherapy, combining viral tumor antigen or …

Cellular metabolism supports immune cell function. Here, we identify a reduction in fatty acid
synthesis and mitochondrial metabolism in dendritic cells (DC) due to α-fetoprotein (AFP), a …

The unique liver immune microenvironment favors resistance to inflammation that promotes
normal physiological function. At the same time, it endows the liver with tolerogenic …

Alpha-fetoprotein (AFP) entrance into cancer cells is mediated by AFP receptors (AFPRs)
and exerts malignant effects. Therefore, understanding the structure of AFPRs will facilitate …

An imidazolium based ionic liquid was successfully prepared and used as an organic ligand
to coordinate with Zn 2+ to prepare trapezoidal metal-organic frameworks (Zn-MOF) …

Recent studies have demonstrated that the carboxyterminal third domain of alpha-
fetoprotein (AFP-CD) binds with various ligands and receptors. Reports within the last …

Hepatocellular carcinoma (HCC) is one of the most common causes of cancer death
worldwide. It usually arises based on a background of chronic liver diseases, defined as the …