Esophageal cancer is one of the most aggressive gastrointestinal cancers. This review
focuses on eight topics within the multidisciplinary approach for esophageal cancer. As …

The primary objective of these guidelines is to provide general clinicians with information
that would guide them to make informed choices of the available diagnosis/treatment …

Background & Aims Surgery is the standard of care for T1bN0M0 esophageal squamous cell
carcinoma (ESCC), whereas chemoradiotherapy (CRT) is a treatment option. This trial …

We investigate whether high-dose (HD,≥ 60 Gy) radiotherapy in definitive concurrent
chemoradiotherapy (CCRT) based on cisplatin could yield benefits compared to …

Background The purpose of this study was to perform a dosimetric comparison between
proton beam therapy (PBT) and photon radiation therapy in patients with locally advanced …

Purpose Definitive chemoradiotherapy (CRT) is the standard treatment for patients with
locally advanced esophageal cancer (EC) who refuse surgery as the initial therapy …

Multidisciplinary treatment comprising surgery, chemotherapy, and radiotherapy for
resectable esophageal squamous cell carcinoma (ESCC) is widely used with improved …

Abstract Background Schlafen 11 (SLFN11) was recently identified as a dominant
determinant of sensitivity to DNA-targeting agents including platinum-based drugs. SLFN11 …

During the past two decades, it has become increasingly clear that the antineoplastic effects
of radiation therapy do not simply reflect the ability of X-, β-and γ-rays to damage …

Simple Summary The standard treatment of choice for inoperable esophageal cancer is
concurrent chemoradiation therapy. However, the treatment effect varies among patients …