Many studies have revealed that circulating long noncoding RNAs (lncRNAs) regulate gene
and protein expression in the process of hepatic fibrosis. Liver fibrosis is a reversible wound …

Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles,
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …

Activation of hepatic stellate cells (HSCs) represents the primary driving force to promote the
progression of chronic cholestatic liver diseases. We previously reported that cholangiocyte …

Currently, resistance to tyrosine kinase inhibitors, such as gefitinib, has become one major
obstacle for improving the clinical outcome of patients with metastatic and advanced‑stage …

Idiosyncratic drug‐induced liver injury (DILI) is a rare, often difficult‐to‐predict adverse
reaction with complex pathomechanisms. However, it is now evident that certain forms of …

Activation of hepatic macrophages represents the critical driving force to promote cholestatic
liver injury. Exosomes, as important small extracellular vesicles released by almost all types …

Long noncoding RNAs (lncRNAs) are pervasively transcribed in the genome, exhibit a
diverse range of biological functions, and exert effects through a variety of mechanisms. The …

Over the last two decades, our understanding of the pathological role of hepatic stellate cells
(HSCs) in fibrotic liver disease has increased dramatically. As HSCs are identified as the …

In the past decade, the study of extracellular vesicles (EVs), especially exosomes (50–150
nm) have attracted growing interest in numerous areas of cancer and tissue regeneration …

The role of long noncoding RNAs (lncRNAs) in the epithelial‐mesenchymal transition (EMT)
in pancreatic ductal adenocarcinoma (PDAC) is unclear. Some lncRNAs can be transferred …