Chemistry and pharmacology of bergenin or its derivatives: A promising molecule

ZM Salimo, MN Yakubu, EL da Silva, ACG de Almeida… - Biomolecules, 2023 - mdpi.com
Bergenin is a glycosidic derivative of trihydroxybenzoic acid that was discovered in 1880 by
Garreau and Machelart from the rhizomes of the medicinal plant Bergenia crassifolia …

Diversity, pharmacology and synthesis of bergenin and its derivatives: Potential materials for therapeutic usages

GB Bajracharya - Fitoterapia, 2015 - Elsevier
Bergenin, a natural secondary metabolite, has been isolated from different parts of a number
of plants. It is one of active ingredients in herbal and Ayurvedic formulations. It exhibits …

Induction of p53 mediated mitochondrial apoptosis and cell cycle arrest in human breast cancer cells by plant mediated synthesis of silver nanoparticles from Bergenia …

MM Faheem, M Bhagat, P Sharma, R Anand - International Journal of …, 2022 - Elsevier
The biological synthesis of nanoparticles is a growing research trend because it has
numerous pharmaceutical and biomedical applications. The present study describes the …

Bergenin Plays an Anti-Inflammatory Role via the Modulation of MAPK and NF-κB Signaling Pathways in a Mouse Model of LPS-Induced Mastitis

X Gao, M Guo, Z Zhang, T Wang, Y Cao, N Zhang - Inflammation, 2015 - Springer
Mastitis is a major disease in humans and other animals and is characterized by mammary
gland inflammation. It is a major disease of the dairy industry. Bergenin is an active …

Anti-oxidative, anti-apoptotic, and anti-inflammatory activities of Connarus semidecandrus Jack ethanol extract in UVB-irradiated human keratinocytes

L Huang, JH Kim, L You, SH Park, J Zhang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Connarus semidecandrus Jack (Family:
connaraceae) is a medicinal plant known for its wide distribution throughout Southeast Asia …

The natural product bergenin ameliorates lipopolysaccharide-induced acute lung injury by inhibiting NF-kappaB activition

S Yang, Z Yu, L Wang, T Yuan, X Wang… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance Bergenin, an active constituent of the plants of the genus
Bergenia, was reported to have anti-inflammatory effects in the treatment of chronic …

Traditional Chinese Herbal Medicine Penthorum chinense Pursh: A Phytochemical and Pharmacological Review

A Wang, L Lin, Y Wang - The American Journal of Chinese Medicine, 2015 - World Scientific
Penthorum chinense Pursh (Ganhuangcao), a traditional Chinese medicine, is used for the
prevention and treatment of liver diseases, including hepatitis B, hepatitis C, and alcoholic …

Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor

BP Pandey, SP Pradhan, K Adhikari… - … Medicine and Therapies, 2020 - Springer
Abstract Background The Bergenia species are perennial herbs native to central Asia, and
one of the most promising medicinal plants of the family Saxifragaceae which are popularly …

A fresh look on bergenin: vision of its novel drug delivery systems and pharmacological activities

S Mehta, V Kadian, S Dalal, P Dalal, S Kumar… - Future …, 2022 - mdpi.com
Bergenin (BER), a key constituent of Bergenia crassifolia (Saxifragaceae), has gained
extensive attention, owing to its array of pharmacological actions, including anti-infective …

Antioxidant and Antiplasmodial Activities of Bergenin and 11‐O‐Galloylbergenin Isolated from Mallotus philippensis

H Khan, H Amin, A Ullah, S Saba… - Oxidative Medicine …, 2016 - Wiley Online Library
Two important biologically active compounds were isolated from Mallotus philippensis. The
isolated compounds were characterized using spectroanalytical techniques and found to be …