Programmed cell death (PCD) or apoptosis is a mechanism which is crucial for all
multicellular organisms to control cell proliferation and maintain tissue homeostasis as well …

Breast cancer has become the most commonly diagnosed cancer globally. The relapse and
metastasis of breast cancer remain a great challenge despite advances in chemotherapy …

The development of immunotherapy agents has revolutionized the field of oncology. The
only FDA-approved immunotherapeutic approach in breast cancer consists of immune …

Breast cancer is immunogenic, and infiltrating immune cells in primary breast tumors convey
important clinical prognostic and predictive information. Furthermore, the immune system is …

Introduction Tumor infiltrating lymphocytes may indicate an immune response to cancer
development, but their significance remains controversial in breast cancer. We conducted …

Increased levels of total tumor-infiltrating lymphocytes (TILs) are generally associated with
good prognosis in several breast cancer subtypes. Subtypes of TILs impact both tumor cells …

Enthusiasm for therapeutic cancer vaccines has been rejuvenated with the recent
completion of several large, randomized phase III clinical trials that in some cases have …

The immune system is active in breast cancer, playing a dual role in tumor progression and
in immune surveillance. Infiltrating immune cells are both prognostic and predictive of …

Background: p53 accumulation in head and neck squamous cell carcinoma (HNSCC) cells
creates a targetable tumor antigen. Adjuvant dendritic cell (DC)–based vaccination against …

In the unique supply chain of cellular therapies, preservation is important to keep the cell
product viable. Many factors in cryopreservation affect the outcome of a cell therapy:(i) …