Alzheimer's disease [AD] is the most common cause of dementia in North America. Despite
30+ years of intense investigation, the field lacks consensus regarding the etiology and …

Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder associated with
progressive loss of cognitive function. 2-[18 F] fluoro-2-deoxy-d-glucose (FDG) positron …

The diagnosis of dementia syndromes can be challenging for clinicians, particularly in the
early stages of disease. Patients with higher education levels may experience a marked …

Alzheimer's disease (AD) is the most common cause of dementia in North America. Growing
evidence supports the concept that AD is fundamentally a metabolic disease that results in …

Atrophy of the medial temporal lobe, especially the hippocampus and the parahippocampal
gyrus, is considered to be the most predictive structural brain biomarker for Alzheimer's …

Atrophy measured on structural magnetic resonance imaging (sMRI) is a powerful biomarker
of the stage and intensity of the neurodegenerative aspect of Alzheimer's disease (AD) …

Background ¹⁸F‐FDFG uptake by brain tissue as measured by positron emission
tomography (PET) is a well‐established method for assessment of brain function in people …

Machine learning methods have successfully been used to predict the conversion of mild
cognitive impairment (MCI) to Alzheimer's disease (AD), by classifying MCI converters (MCI …

Hippocampal atrophy, posterior cingulate and frontal glucose hypometabolism, and white-
matter tract disruption are well described early macroscopic events in Alzheimer's disease …

The complexity of Alzheimer's disease (AD) and its long prodromal phase poses challenges
for early diagnosis and yet allows for the possibility of the development of disease modifying …