Strategies for making high‐performance artificial spider silk fibers

B Schmuck, G Greco, TB Pessatti… - Advanced Functional …, 2024 - Wiley Online Library
Artificial spider silk is an attractive material for many technical applications since it is a
biobased fiber that can be produced under ambient conditions but still outcompetes …

A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications

DB Kell, GJ Laubscher, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Post-acute sequelae of COVID (PASC), usually referred to as 'Long COVID'(a phenotype of
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …

The protein folding problem: the role of theory

R Nassar, GL Dignon, RM Razban, KA Dill - Journal of molecular biology, 2021 - Elsevier
The protein folding problem was first articulated as question of how order arose from
disorder in proteins: How did the various native structures of proteins arise from interatomic …

[HTML][HTML] Atomic force microscopy for single molecule characterisation of protein aggregation

FS Ruggeri, T Šneideris, M Vendruscolo… - Archives of biochemistry …, 2019 - Elsevier
The development of atomic force microscopy (AFM) has opened up a wide range of novel
opportunities in nanoscience and new modalities of observation in complex biological …

Self-assembly of aramid amphiphiles into ultra-stable nanoribbons and aligned nanoribbon threads

T Christoff-Tempesta, Y Cho, DY Kim, M Geri… - Nature …, 2021 - nature.com
Small-molecule self-assembly is an established route for producing high-surface-area
nanostructures with readily customizable chemistries and precise molecular organization …

Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins

J Lim, H Park, J Heisler, T Maculins, M Roose-Girma… - elife, 2019 - elifesciences.org
RIPK1, RIPK3, ZBP1 and TRIF, the four mammalian proteins harboring RIP homotypic
interaction motif (RHIM) domains, are key components of inflammatory signaling and …

Microbial nanowires for sustainable electronics

MJ Guberman-Pfeffer, NM Dorval Courchesne… - Nature Reviews …, 2024 - nature.com
Microbial protein nanowires are emerging as an alternative to abiotic nanowires for
electronics applications. Microbial nanowires are sustainably produced, robust, non-toxic …

HSPA8 acts as an amyloidase to suppress necroptosis by inhibiting and reversing functional amyloid formation

E Wu, W He, C Wu, Z Chen, S Zhou, X Wu, Z Hu, K Jia… - Cell Research, 2023 - nature.com
Ultra-stable fibrous structure is a hallmark of amyloids. In contrast to canonical disease-
related amyloids, emerging research indicates that a significant number of cellular amyloids …

Self-assembling peptide hydrogels for the stabilization and sustained release of active Chondroitinase ABC in vitro and in spinal cord injuries

A Raspa, L Carminati, R Pugliese, F Fontana… - Journal of Controlled …, 2021 - Elsevier
Activated microglia/macrophages infiltration, astrocyte migration, and increased production
of inhibitory chondroitin sulfate proteoglycans (CSPGs) are standard harmful events taking …

Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling

M Samie, J Lim, E Verschueren, JM Baughman… - Nature …, 2018 - nature.com
Defective autophagy is linked to diseases such as rheumatoid arthritis, lupus and
inflammatory bowel disease (IBD). However, the mechanisms by which autophagy limits …