Strategies for making high‐performance artificial spider silk fibers
Artificial spider silk is an attractive material for many technical applications since it is a
biobased fiber that can be produced under ambient conditions but still outcompetes …
biobased fiber that can be produced under ambient conditions but still outcompetes …
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications
DB Kell, GJ Laubscher, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Post-acute sequelae of COVID (PASC), usually referred to as 'Long COVID'(a phenotype of
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …
The protein folding problem: the role of theory
The protein folding problem was first articulated as question of how order arose from
disorder in proteins: How did the various native structures of proteins arise from interatomic …
disorder in proteins: How did the various native structures of proteins arise from interatomic …
[HTML][HTML] Atomic force microscopy for single molecule characterisation of protein aggregation
The development of atomic force microscopy (AFM) has opened up a wide range of novel
opportunities in nanoscience and new modalities of observation in complex biological …
opportunities in nanoscience and new modalities of observation in complex biological …
Self-assembly of aramid amphiphiles into ultra-stable nanoribbons and aligned nanoribbon threads
Small-molecule self-assembly is an established route for producing high-surface-area
nanostructures with readily customizable chemistries and precise molecular organization …
nanostructures with readily customizable chemistries and precise molecular organization …
Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins
J Lim, H Park, J Heisler, T Maculins, M Roose-Girma… - elife, 2019 - elifesciences.org
RIPK1, RIPK3, ZBP1 and TRIF, the four mammalian proteins harboring RIP homotypic
interaction motif (RHIM) domains, are key components of inflammatory signaling and …
interaction motif (RHIM) domains, are key components of inflammatory signaling and …
Microbial nanowires for sustainable electronics
MJ Guberman-Pfeffer, NM Dorval Courchesne… - Nature Reviews …, 2024 - nature.com
Microbial protein nanowires are emerging as an alternative to abiotic nanowires for
electronics applications. Microbial nanowires are sustainably produced, robust, non-toxic …
electronics applications. Microbial nanowires are sustainably produced, robust, non-toxic …
HSPA8 acts as an amyloidase to suppress necroptosis by inhibiting and reversing functional amyloid formation
E Wu, W He, C Wu, Z Chen, S Zhou, X Wu, Z Hu, K Jia… - Cell Research, 2023 - nature.com
Ultra-stable fibrous structure is a hallmark of amyloids. In contrast to canonical disease-
related amyloids, emerging research indicates that a significant number of cellular amyloids …
related amyloids, emerging research indicates that a significant number of cellular amyloids …
Self-assembling peptide hydrogels for the stabilization and sustained release of active Chondroitinase ABC in vitro and in spinal cord injuries
A Raspa, L Carminati, R Pugliese, F Fontana… - Journal of Controlled …, 2021 - Elsevier
Activated microglia/macrophages infiltration, astrocyte migration, and increased production
of inhibitory chondroitin sulfate proteoglycans (CSPGs) are standard harmful events taking …
of inhibitory chondroitin sulfate proteoglycans (CSPGs) are standard harmful events taking …
Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling
Defective autophagy is linked to diseases such as rheumatoid arthritis, lupus and
inflammatory bowel disease (IBD). However, the mechanisms by which autophagy limits …
inflammatory bowel disease (IBD). However, the mechanisms by which autophagy limits …