In addition to the typical respiratory response, new coronavirus disease 2019 (COVID-19) is
also associated with very common gastrointestinal symptoms. Cases with gastrointestinal …

Threonine (Thr), an essential amino acid for animals and the limiting amino acid in swine
and poultry diets, which plays a vital role in the modulation of nutritional metabolism …

Anatomically modern humans interbred with Neanderthals and with a related archaic
population known as Denisovans. Genomes of several Neanderthals and one Denisovan …

The chemokine superfamily consists of a large number of ligands and receptors. At first
glance, this family appears redundant and their ligand-receptor relationships promiscuous …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Influenza in humans is often accompanied by gastroenteritis-like symptoms such as
diarrhea, but the underlying mechanism is not yet understood. We explored the occurrence …

Leukocyte trafficking to the small and large intestines is tightly controlled to maintain
intestinal immune homeostasis, mediate immune responses, and regulate inflammation. A …

Celiac disease has become one of the best-understood HLA-linked disorders. Although it
shares many immunologic features with inflammatory bowel disease, celiac disease is …

The nature and role of the intestinal leukocytes in necrotizing enterocolitis (NEC), a severe
disease affecting premature infants, remain unknown. We now show that the intestine in …

Advances in cancer immunotherapy have offered new hope for patients with metastatic
disease. This unfolding success story has been exemplified by a growing arsenal of novel …