Bioorthogonal cleavage chemistry has been rapidly emerging as a powerful tool for
manipulation and gain-of-function studies of biomolecules in living systems. While the initial …

Inorganic nanoparticles provide multipurpose platforms for a broad range of delivery
applications. Intrinsic nanoscopic properties provide access to unique magnetic and optical …

The transformational impact of bioorthogonal chemistries has inspired new strategies for the
in vivo synthesis of bioactive agents through non-natural means. Among these, Pd catalysts …

Bioorthogonal catalysis using transition-metal catalysts (TMCs) provides a toolkit for the in
situ generation of imaging and therapeutic agents in biological environments. Integrating …

Bioorthogonal chemistry refers to any chemical reactions that can occur inside of living
systems without interfering with native biochemical processes, which has become a …

Considering the intrinsic toxicities of transition metals, their incorporation into drug therapies
must operate at minimal amounts while ensuring adequate catalytic activity within complex …

The incorporation of abiotic transition metal catalysis into the chemical biology space has
significantly expanded the tool kit of bioorthogonal chemistries accessible for cell culture …

In recent decade, palladium-based (Pd-based) nanomaterials have shown significant
potential for biomedical applications because of their unique optical properties, excellent …

Substrate selectivity is one of the most attractive features of natural enzymes from their “bind-
to-catalyze” working flow and is thus a goal for the development of synthetic enzyme mimics …

An emerging approach in the field of targeted drug delivery is the establishment of abiotic
metal‐triggered prodrug mechanisms that can control the release of bioactive drugs …