Gelsolin, an actin-depolymerizing protein expressed both in extracellular fluids and in the
cytoplasm of a majority of human cells, has been recently implicated in a variety of both …

HIV/AIDS is still a global threat despite the notable efforts made by the scientific and health
communities to understand viral infection, to design new drugs or to improve existing ones …

Viruses manipulate host factors to enhance their replication and evade cellular restriction.
We used multiplex tandem mass tag (TMT)-based whole cell proteomics to perform a …

While significant progress has been made in terms of human immunodeficiency virus (HIV)
therapy, treatment does not represent a cure and remains inaccessible to many people …

HIV-1 has evolved a plethora of strategies to overcome the cytoskeletal barrier (ie, actin and
intermediate filaments (AFs and IFs) and microtubules (MTs)) to achieve the viral cycle. HIV …

Chemokines are small chemotactic cytokines that are involved in the regulation of immune
cell migration. Multiple functional properties of chemokines, such as pro-inflammation …

The transactive response DNA-binding protein (TARDBP/TDP-43) influences the processing
of diverse transcripts, including that of histone deacetylase 6 (HDAC6). Here, we assessed …

ABSTRACT A small group of HIV-1-infected individuals, called long-term nonprogressors
(LTNPs), and in particular a subgroup of LTNPs, elite controllers (LTNP-ECs), display …

Viral replication and spreading are fundamental events in the viral life cycle, accounting for
the assembly and egression of nascent virions, events that are directly associated with viral …

The human immunodeficiency virus type 1 (HIV‐1) is an intracellular pathogen whose
replication cycle strictly depends on the host cell molecular machinery. HIV‐1 crosses twice …