[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome
R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
Evaluation and management of adults with obstructive sleep apnea syndrome
JJ Lee, KM Sundar - Lung, 2021 - Springer
Obstructive sleep apnea syndrome (OSAS) is a common and underdiagnosed medical
condition characterized by recurrent sleep-dependent pauses and reductions in airflow …
condition characterized by recurrent sleep-dependent pauses and reductions in airflow …
Intermittent hypoxemia and OSA: implications for comorbidities
NA Dewan, FJ Nieto, VK Somers - Chest, 2015 - Elsevier
OSA is a common chronic disorder that is associated with significant morbidity and mortality
including cardiovascular, metabolic, and neurocognitive disease and increased cancer …
including cardiovascular, metabolic, and neurocognitive disease and increased cancer …
Oxidative stress in obstructive sleep apnea and intermittent hypoxia–revisited–the bad ugly and good: implications to the heart and brain
L Lavie - Sleep medicine reviews, 2015 - Elsevier
Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), is linked with
increased reactive oxygen species/reactive nitrogen species (ROS/RNS) and oxidative …
increased reactive oxygen species/reactive nitrogen species (ROS/RNS) and oxidative …
[HTML][HTML] Acute vs. chronic vs. cyclic hypoxia: their differential dynamics, molecular mechanisms, and effects on tumor progression
K Saxena, MK Jolly - Biomolecules, 2019 - mdpi.com
Hypoxia has been shown to increase the aggressiveness and severity of tumor progression.
Along with chronic and acute hypoxic regions, solid tumors contain regions of cycling …
Along with chronic and acute hypoxic regions, solid tumors contain regions of cycling …
Obstructive sleep apnoea syndrome
Obstructive sleep apnoea syndrome (OSAS) is a common clinical condition in which the
throat narrows or collapses repeatedly during sleep, causing obstructive sleep apnoea …
throat narrows or collapses repeatedly during sleep, causing obstructive sleep apnoea …
Cycling hypoxia: A key feature of the tumor microenvironment
C Michiels, C Tellier, O Feron - … et Biophysica Acta (BBA)-Reviews on …, 2016 - Elsevier
A compelling body of evidence indicates that most human solid tumors contain hypoxic
areas. Hypoxia is the consequence not only of the chaotic proliferation of cancer cells that …
areas. Hypoxia is the consequence not only of the chaotic proliferation of cancer cells that …
Hypoxia-inducible factors and cancer
Abstract Purpose of Review Hypoxia-inducible factors (HIFs) mediate the transcription of
hundreds of genes that allow cells to adapt to hypoxic environments. In this review, we …
hundreds of genes that allow cells to adapt to hypoxic environments. In this review, we …
Sleep apnea and cancer: analysis of a nationwide population sample
D Gozal, SA Ham, B Mokhlesi - sleep, 2016 - academic.oup.com
Abstract Study Objectives: Epidemiological evidence from relatively small cohorts suggests
that obstructive sleep apnea (OSA) is associated with higher cancer incidence and mortality …
that obstructive sleep apnea (OSA) is associated with higher cancer incidence and mortality …
Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer
I Hunyor, KM Cook - American Journal of Physiology …, 2018 - journals.physiology.org
Obstructive sleep apnea (OSA) is common and linked to a variety of poor health outcomes. A
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …